Results 291 to 300 of about 299,250 (314)
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Mimicry, deception and competition: The life of competing endogenous RNAs

WIREs RNA, 2019
Since their discovery, small regulatory RNAs (sRNAs) were thought to be regulated exclusively at the transcriptional level. However, accumulating data from recent reports indicate that posttranscriptional signals can also modulate the function and stability of sRNAs.
Marc P, Grüll, Eric, Massé
openaire   +2 more sources

Competing Endogenous RNAs (CeRNAs): Novel Network in Neurological Disorders

Current Medicinal Chemistry, 2021
Neurological disorders (NDs) comprise a broad range of diseases affecting both central and peripheral nervous systems. These complex multifactorial diseases have a high rate of mortality all over the world, particularly in aged people. Today, new evidence drove our attention to the notable role of noncoding RNAs (ncRNAs) in the progression of NDs ...
Sadra Samavarchi Tehrani   +7 more
openaire   +2 more sources

Characterization of conditions for competing endogenous RNA regulation in GBM

2013 IEEE International Workshop on Genomic Signal Processing and Statistics, 2013
Summary form only given. MicroRNAs (miRNAs) are short non-coding RNAs with the average length of 22 nucleotides. They are known to induce mRNA degradation or suppression of translation by complementarily binding to 3' untranslated regions (3' UTRs) of target mRNA transcripts.
Yu-Chiao Chiu   +3 more
openaire   +1 more source

Identification of dysregulated competing endogenous RNA networks in glioblastoma: A way toward improved therapeutic opportunities.

Life Science, 2021
Glioblastoma is recognized as one of the leading causes of death worldwide. Although there have been considerable advancements in understanding the causative molecular mechanisms of this malignancy, effective therapeutic strategies are still in limited ...
Saghar Rahnama   +5 more
semanticscholar   +1 more source

Long non-coding RNA H19 and cancer: A competing endogenous RNA

Bulletin du Cancer, 2019
Long non-coding RNA (lncRNA) is a class of non-coding RNA with a length of more than 200 nucleotides, which has become a hotspot in the research of tumorigenesis and development in recent years. Accumulating studies have indicated that H19 is abnormally expressed in human malignant tumors, and regulates cell proliferation, migration, invasion, anti ...
Yafen, Ye, Ao, Shen, Anwen, Liu
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CircRNA-104718 acts as competing endogenous RNA and promotes hepatocellular carcinoma progression through microRNA-218-5p/TXNDC5 signaling pathway.

Clinical science, 2019
Accumulating evidences indicate that circular RNAs (circRNAs) play a vital role in diverse cancer biology. However, the contributions of circRNAs to hepatocellular carcinoma (HCC) and their underlying mechanism remain largely unknown.
Jiaze Yu   +6 more
semanticscholar   +1 more source

Roles of microRNAs and prospective view of competing endogenous RNAs in mycotoxicosis

Mutation Research/Reviews in Mutation Research, 2019
Mycotoxins, produced by fungi, are secondary metabolites causing adverse, toxic and pathological effects on human and animals. Studies about the association between mycotoxins and microRNAs (miRNAs) were developed since miRNAs have been demonstrated to play a critical role in many developmental processes for regulating messenger RNA (mRNA).
Yuxiao Liao   +5 more
openaire   +2 more sources

Competing Endogenous RNA and Interactome Bioinformatic Analyses on Human Telomerase

Rejuvenation Research, 2014
We present a classic interactome bioinformatic analysis and a study on competing endogenous (ce) RNAs for hTERT . The hTERT gene codes for the catalytic subunit and limiting component of the human telomerase complex.
Walter, Arancio   +4 more
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[Research progress of competing endogenous RNA].

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
The competing endogenous RNA (ceRNA) hypothesis is a new pattern of gene posttranscriptional regulation. Encoding mRNA, long noncoding RNA (lncRNA), pseudogene transcript, circular RNA (circRNA), etc. can regulate gene expression by binding microRNA (miRNA).
Lin, Wang, Jie, Liu
openaire   +1 more source

[New mode of competing endogenous RNA: circular RNA].

Zhonghua wei zhong bing ji jiu yi xue, 2018
Circular RNA (circRNA) is widely found in various species' cells.They have several characteristics including structural stability,high expression and expression in a tissue-specific manner.Recent studies have demonstrated that circRNA is a member of competing endogenous RNA (ceRNA).CircRNA regulate the expression of related RNA molecules via binding ...
openaire   +1 more source

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