Results 221 to 230 of about 81,616 (246)

Noncoding RNA-Associated Competing Endogenous RNA Networks in Doxorubicin-Induced Cardiotoxicity

DNA and Cell Biology, 2022
Accumulating evidence has indicated that noncoding RNAs (ncRNAs) are involved in doxorubicin-induced cardiotoxicity (DIC). However, the ncRNA-associated competing endogenous RNA (ceRNA)-mediated regulatory mechanisms in DIC remain unclear. In this study, we aimed to systematically investigate the alterations in expression levels of long noncoding RNA ...
Zijun Xiao, Shanshan Wei, Jie Huang, Jiaqin Liu, Jian Liu, Bikui Zhang, Wenqun Li   +6 more
openaire   +2 more sources

Modeling competing endogenous RNA regulatory networks in glioblastoma multiforme

2013 IEEE International Conference on Bioinformatics and Biomedicine, 2013
Recent studies postulated that genes harboring identical microRNA (miRNA) binding sites can crosstalk by competing for a limited pool of the binding miRNAs (the miRNA program), named as the regulation of competing endogenous RNAs (ceRNAs). Incorporating recent biological evidence that ceRNA regulation depends on miRNA program expression levels, we ...
Yu-Chiao Chiu, Eric Y. Chuang, Tzu-Hung Hsiao, Yidong Chen 0002   +3 more
openaire   +1 more source

Identification of competing endogenous RNA network in laryngeal squamous cell carcinoma

Oral Diseases, 2021
AbstractObjectiveThis study was conducted to investigate key long noncoding RNAs (lncRNAs) involved in competitive endogenous RNA (ceRNA) network associated with laryngeal squamous cell carcinoma (LSCC).Materials and MethodsThree mRNA datasets, two miRNA datasets, and one lncRNA dataset of LSCC were downloaded from GEO database.
Xiao‐Feng Cui, Si‐Lin Zhang, Wei‐Ping Wang, Xiao‐Wu Huang, Xiang‐Jun Chen   +4 more
openaire   +2 more sources

A New Network-Based Tool to Analyse Competing Endogenous RNAs

2020
Interactions between microRNA targets are defined as competing endogenous RNAs. After discovery of the repressive activity of microRNAs with different mechanisms, various experimental or computational approaches have been developed to understand the relationships among their targets.
Selcen Ari Yuka, Alper Yilmaz 0003
openaire   +2 more sources

Identification of the Competing Endogenous RNA Networks in Oxidative Stress Injury of Melanocytes

DNA and Cell Biology, 2021
Competing endogenous RNAs (ceRNAs), including long noncoding RNA (lncRNA), circular RNA (circRNA), pseudogenes, synthetic miRNA inhibitors, etc. are classes of RNAs that can compete and interact with each other within an organism.
Si, Li, Hongliang, Zeng, Jinhua, Huang, Jianyun, Lu, Jing, Chen, Ying, Zhou, Lan, Mi, Xiaojiao, Zhao, Li, Lei, Qinghai, Zeng   +9 more
openaire   +2 more sources

Integrated analysis of long noncoding RNA‐associated competing endogenous RNA network in periodontitis

Journal of Periodontal Research, 2018
Background and ObjectivesLong noncoding RNAs (lncRNAs) play critical and complex roles in regulating various biological processes of periodontitis. This bioinformatic study aims to construct a putative competing endogenous RNA (ceRNA) network by integrating lncRNA, miRNA and mRNA expression, based on high‐throughput RNA sequencing and microarray data ...
S. Li, X. Liu, H. Li, H. Pan, A. Acharya, Y. Deng, Y. Yu, R. Haak, J. Schmidt, G. Schmalz, D. Ziebolz   +10 more
openaire   +4 more sources

Competing endogenous RNA networks in cervical cancer: function, mechanism and perspective

Journal of Drug Targeting, 2019
In the past several years, competing endogenous RNAs (ceRNAs) have emerged as a potential class of post-transcriptional regulators that alter gene expression through a microRNA (miRNA)-mediated mechanism. An increasing number of studies have found that ceRNAs play important roles in tumorigenesis.
Hui, Du, Ying, Chen
openaire   +2 more sources

A fishnet between nasopharyngeal carcinoma and resistance: the competing endogenous RNA network

Current Treatment Options in Oncology
Chemotherapy and radiotherapy (chemo-/radiotherapy) have advanced as the main treatment modalities for nasopharyngeal carcinoma (NPC), improving patient survival rates. However, chemo-/radiotherapy resistance in NPC cells has emerged as a key factor contributing to poor prognosis.
Mingtai, Li, Tongtong, Mo, Zisha, Yang, Yunhong, Yao, Yan, Wang, Yi, Zhao   +5 more
openaire   +2 more sources

Competing endogenous RNA network in pulmonary arterial hypertension

International Journal of Cardiology, 2014
Kai, Ma, Qian, Zhao, Shoujun, Li
openaire   +2 more sources

Development of an immune‐related lncRNA–miRNA–mRNA network based on competing endogenous RNA in periodontitis

Journal of Clinical Periodontology, 2021
Han Tang, Ping Ji
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