Results 61 to 70 of about 767,407 (301)
The relevance of non-formal Biology Olympiad training for upper secondary school students
LUMAT, 2018 Science competitions, such as the International Biology Olympiad, are non-formal education targeted to upper secondary school students with high abilities.
Justus Mutanen, Maija Aksela
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Scinapse 2019-2020 Undergraduate Science Case Competition: Augmented Biology
Undergraduate Research in Natural and Clinical Science and Technology (URNCST) Journal, 2020 The Scinapse Undergraduate Science Case Competition (USCC) provides an opportunity for undergraduate students to experience the development of a novel research proposal. A case is presented to all participants and, using in-depth literature search (publications, reports, studies and published writings), students connect and pinpoint key ...
Clarissa Ngo +2 more
openaire +2 more sources
Use of sigma factor M from Bacillus subtilis in the development of an orthogonal expression system in Escherichia coli [PDF]
, 2014 Background: Technological advances in synthetic biology, systems biology, and metabolic engineering have boosted applications of industrial biotechnology for an increasing number of complex and high added-value molecules.
Bervoets, Indra +2 more
core
LAG3’s Enigmatic Mechanism of Action
Frontiers in Immunology, 2021 LAG3 is an important immune checkpoint with relevance in cancer, infectious disease and autoimmunity. However, despite LAG3’s role in immune exhaustion and the great potential of LAG3 inhibition as treatment, much remains unknown about its biology ...
Colin G. Graydon +5 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Biosfer, 2021 Scientific reasoning and problem-solving have become primary interests in 21st-century education. These skills have an essential role in preparing students to face global competition.
Maisuna Kundariati +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Cultivation of Synthetic Biology with the iGEM Competition
Journal of Advanced Computational Intelligence and Intelligent Informatics, 2013 The main goal of synthetic biology is to create new biological modules that augment or modify the behavior of living organisms in performing different tasks. These modules are useful in a wide range of applications, such as medicine, agriculture, energy and environmental remediation.
Thamamongood, Thiprampai +5 more
openaire +2 more sources