Exact concentration regions for stimulus-switched competitive binding under finite depletion [PDF]
Transferring binary binding constants into competitive mixtures is a common but rarely validated step in stimulus-programmed molecular recognition. A pH-programmed Co8L12 coordination cage reported by Cullen et al., Chem.
Hyun Seo
doaj +2 more sources
IGF UPTAKE WITH COMPETITIVE BINDING IN ARTICULAR CARTILAGE [PDF]
Experiments on the transport of radiolabeled Insulin-like Growth Factors (IGF-I and -II) into bovine articular cartilage show differential uptake depending on the relative proportion of IGF-I and -II. In this study, we present a mathematical model describing both the transport and competition of IGF-I and -II for binding sites represented by two ...
Zhang, Lihai +4 more
openaire +3 more sources
Citation: 'competitive binding assay' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.C01199 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
Valentina Elisabetta Viviana Ferrero (606399) +6 more
openaire +2 more sources
bindNode24: Competitive binding residue prediction with 60 % smaller model [PDF]
Many proteins function through ligand binding. Yet, reliable experimental binding data remains limited. Recent advances predict binding residues from sequences using protein Language Model embeddings.
Kyra Erckert +2 more
doaj +2 more sources
Probiotics mitigate non-antibiotic drug-induced dysbiosis via protein homology-driven competitive binding [PDF]
While the impact of non-antibiotic drugs on gut bacteria is well-known, their mechanisms of action remain poorly characterized, and effective mitigation strategies for drug-induced dysbiosis are still limited.
Shuo Feng +20 more
doaj +2 more sources
CLASP-mediated competitive binding in protein condensates directs microtubule growth [PDF]
Microtubule organization in cells relies on targeting mechanisms. Cytoplasmic linker proteins (CLIPs) and CLIP-associated proteins (CLASPs) are key regulators of microtubule organization, yet the underlying mechanisms remain elusive. Here, we reveal that
Xuanyan Jia +11 more
doaj +2 more sources
Competitive interactions of ligands and macromolecular crowders with maltose binding protein. [PDF]
Cellular signaling involves a cascade of recognition events occurring in a complex environment with high concentrations of proteins, polysaccharides, and other macromolecules.
Andrew C Miklos +2 more
doaj +2 more sources
Competitive ligand binding kinetics to linear polymers [PDF]
Different types of ligands compete in binding to polymers with different consequences for the physical and chemical properties of the resulting complex.
Villaluenga, Juan P. G. +4 more
core +2 more sources
The role of surface glycoconjugates in Leishmania midgut attachment examined by competitive binding assays and experimental development in sand flies [PDF]
SUMMARY Binding of promastigotes to the sand fly midgut epithelium is regarded as an essential part of the Leishmania life cycle in the vector. Among Leishmania surface molecules putatively involved in attachment to the sand fly midgut, two GPI-anchored ...
Jecna, Lucie +6 more
core +5 more sources
Competitive aptamer switch for modulating ligand binding affinity
Aptamers are short, single-stranded DNA or RNA molecules that selectively bind to a target molecule. Aptamer-complement duplex (ACD) is often used to design molecular switches capable of producing a detectable signal or triggering a structural change ...
Derek Puyat +3 more
doaj +1 more source

