Results 261 to 270 of about 110,378 (294)
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Competitive endogenous RNA in colorectal cancer: A systematic review
Gene, 2018Colorectal cancer is one of the most common malignant tumours. Competitive endogenous RNA (ceRNA) networks have been hypothesized, in which various RNAs regulate each other's expression using microRNA response elements (MREs). Recent evidence has highlighted the crucial regulatory roles of ceRNA networks in colorectal cancer.
Han Shuwen +3 more
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Pseudogenes as Competitive Endogenous RNAs: Target Prediction and Validation
2014Pseudogenes may regulate expression of their parental genes as well as other protein-coding genes through various mechanisms. One such mechanism is the ability to act as competitive endogenous RNA (ceRNA) and participate in microRNA-mediated cross-regulation.
Karreth, Florian A. +3 more
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Mimicry, deception and competition: The life of competing endogenous RNAs
WIREs RNA, 2019Since their discovery, small regulatory RNAs (sRNAs) were thought to be regulated exclusively at the transcriptional level. However, accumulating data from recent reports indicate that posttranscriptional signals can also modulate the function and stability of sRNAs.
Marc P, Grüll, Eric, Massé
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Competitive endogenous RNA network: potential implication for systemic lupus erythematosus
Expert Opinion on Therapeutic Targets, 2017Competitive endogenous RNA (ceRNA) hypothesis proposes that RNA transcripts, both coding and non-coding, crosstalk with and coregulate each other using microRNA response elements (MREs). CeRNA analysis tremendously expands functional information of coding and non-coding RNAs.
Lian-Ju, Li +6 more
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Interdisciplinary Sciences: Computational Life Sciences, 2021
This study was aimed to identify biomarker associated with membranous nephropathy (MN) progression by integration of expression profiles and competitive endogenous RNA (ceRNA) network analysis.The gene (GSE108113) and microRNAs (miRNAs) expression profiles (GSE64306) were downloaded to identify the differentially expressed mRNAs, miRNAs and long non ...
Guangyu, Zhou +4 more
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This study was aimed to identify biomarker associated with membranous nephropathy (MN) progression by integration of expression profiles and competitive endogenous RNA (ceRNA) network analysis.The gene (GSE108113) and microRNAs (miRNAs) expression profiles (GSE64306) were downloaded to identify the differentially expressed mRNAs, miRNAs and long non ...
Guangyu, Zhou +4 more
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Sp1 is a competitive endogenous RNA of Klf4 during odontoblast differentiation
The International Journal of Biochemistry & Cell Biology, 2017Our previous studies have demonstrated that KLF4 is a critical transcription factor that promotes the odontoblastic differentiation of dental papilla cells. Klf4 mRNA was found to be regulated by multiple microRNAs (miRNAs). Competitive endogenous RNAs (ceRNAs) are a group of transcripts post-transcriptionally regulating each other by competing for ...
Jie, Zhang +7 more
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Cancer Gene Therapy, 2021
Accumulating evidence shows that circular RNA (circRNA) is an important regulator of many diseases, especially cancer. Gastric cancer (GC) is a malignant tumor of the digestive system. The regulatory role and potential mechanism of circRNAs in GC remain unknown.
Tong Han +4 more
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Accumulating evidence shows that circular RNA (circRNA) is an important regulator of many diseases, especially cancer. Gastric cancer (GC) is a malignant tumor of the digestive system. The regulatory role and potential mechanism of circRNAs in GC remain unknown.
Tong Han +4 more
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Clinical and Experimental Medicine, 2020
To investigate lncRNAs acting as competing endogenous RNAs (ceRNAs) involved in oncogenesis and progression of HCC. Different expressed lncRNAs, microRNAs, and mRNAs (DElncRNAs, DEmiRNAs, DEmRNAs), downloaded from The Cancer Genome Atlas (TCGA) database, were identified by edgeR package.
Lili Qu +8 more
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To investigate lncRNAs acting as competing endogenous RNAs (ceRNAs) involved in oncogenesis and progression of HCC. Different expressed lncRNAs, microRNAs, and mRNAs (DElncRNAs, DEmiRNAs, DEmRNAs), downloaded from The Cancer Genome Atlas (TCGA) database, were identified by edgeR package.
Lili Qu +8 more
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The BRAF Pseudogene Is a Proto-Oncogenic Competitive Endogenous RNA
Blood, 2014Abstract Non-coding RNAs have long been viewed as non-functional genomic relicts of evolution, but recetn findings have implicated their importance in physiology and disease. Recently, in vitro experiments demonstrated that the pseudogenes of PTEN and KRAS operate as natural miRNA decoys (competitive endogenous RNAs or ceRNAs) that ...
Florian Karreth +5 more
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Current Gene Therapy, 2019
Liver fibrosis or scarring is the most common pathological feature caused by chronic liver injury, and is widely considered one of the primary causes of morbidity and mortality. It is primarily characterised by hepatic stellate cells (HSC) activation and excessive extracellular matrix (ECM) protein deposition.
Farooq, Riaz, Dongmin, Li
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Liver fibrosis or scarring is the most common pathological feature caused by chronic liver injury, and is widely considered one of the primary causes of morbidity and mortality. It is primarily characterised by hepatic stellate cells (HSC) activation and excessive extracellular matrix (ECM) protein deposition.
Farooq, Riaz, Dongmin, Li
openaire +2 more sources