Results 271 to 280 of about 110,378 (294)
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The development and controversy of competitive endogenous RNA hypothesis in non-coding genes

Molecular and Cellular Biochemistry, 2020
As a momentous post-transcriptional regulator, microRNAs (miRNAs) are attracting more and more attention. The classical miRNAs regulated mechanism shows it binds to the targets' 3'UTR thus play the role in post-transcription. Meanwhile, single miRNA can target multiple genes, so those should compete to bind that miRNA.
Weimin Lin   +6 more
openaire   +2 more sources

Immune-Related Hub Genes and the Competitive Endogenous RNA Network in Alzheimer’s Disease

Journal of Alzheimer’s Disease, 2020
Background: The pathogenesis of Alzheimer’s disease (AD) involves various immune-related phenomena; however, the mechanisms underlying these immune phenomena and the potential hub genes involved therein are unclear. An understanding of AD-related immune hub genes and regulatory mechanisms would help develop new immunotherapeutic targets. Objective: The
Hui, Xu, Jianping, Jia
openaire   +2 more sources

m6A RNA methylation regulates the fate of endogenous retroviruses

Nature, 2021
Tomasz Chelmicki   +2 more
exaly  

A Roadmap for the Computational Prediction and Experimental Validation of Competitive Endogenous RNAs

2019
MicroRNAs (miRNAs) are fine-tuners of gene expression and contribute to the regulation of most, if not all, biological processes in eukaryotes by targeting both coding and noncoding RNAs. Typically, miRNAs repress numerous target transcripts and most target RNAs harbor binding sites for multiple miRNA families. It was recently proposed that transcripts
openaire   +2 more sources

A-to-I editing prevents self-RNA sensing

Nature Reviews Molecular Cell Biology, 2022
Leilei Chen
exaly  

CLUSTER guide RNAs enable precise and efficient RNA editing with endogenous ADAR enzymes in vivo

Nature Biotechnology, 2022
Ngadhnjim Latifi   +2 more
exaly  

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