Results 41 to 50 of about 3,211,899 (373)
Robust Orthogonal Complement Principal Component Analysis [PDF]
, 2016 Recently, the robustification of principal component analysis has attracted lots of attention from statisticians, engineers and computer scientists. In this work we study the type of outliers that are not necessarily apparent in the original observation ...
Li, Shijie, She, Yiyuan, Wu, Dapeng
core +1 more source
A Review of Complement Activation in SLE
Current Rheumatology Reports, 2021 Purpose of Review Complement activation is a key event in the pathogenesis of tissue inflammation and injury in systemic lupus erythematosus (SLE). This review is aimed at comparing the usefulness of measurement of complement proteins in serum/plasma (C3,
A. Weinstein, R. Alexander, D. Zack
semanticscholar +1 more source
A complement to Le Cam's theorem [PDF]
, 2007 This paper examines asymptotic equivalence in the sense of Le Cam between density estimation experiments and the accompanying Poisson experiments. The significance of asymptotic equivalence is that all asymptotically optimal statistical procedures can be
Low, Mark G., Zhou, Harrison H.
core +3 more sources
Tipping the balance: intricate roles of the complement system in disease and therapy
Seminars in Immunopathology, 2021 The ability of the complement system to rapidly and broadly react to microbial intruders, apoptotic cells and other threats by inducing forceful elimination responses is indispensable for its role as host defense and surveillance system.
R. Pouw, Daniel Ricklin
semanticscholar +1 more source
On the lattice of subgroups of a free group: complements and rank
, 2020 A $\vee$-complement of a subgroup $H \leqslant \mathbb{F}_n$ is a subgroup $K \leqslant \mathbb{F}_n$ such that $H \vee K = \mathbb{F}_n$. If we also ask $K$ to have trivial intersection with $H$, then we say that $K$ is a $\oplus$-complement of $H$. The
Delgado, Jordi, Silva, Pedro V.
core +1 more source
Engineering novel complement activity into a pulmonary surfactant protein [PDF]
, 2010 Complement neutralizes invading pathogens, stimulates inflammatory and adaptive immune responses, and targets non- or altered-self structures for clearance.
Anthony H. Keeble +38 more
core +2 more sources
Altered heme-mediated modulation of dendritic cell function in sickle cell alloimmunization
Haematologica, 2016 Transfusions are the main treatment for patients with sickle cell disease. However, alloimmunization remains a major life-threatening complication for these patients, but the mechanism underlying pathogenesis of alloimmunization is not known.
Emmanuelle Godefroy +7 more
doaj +1 more source
Complement in neurological disorders and emerging complement-targeted therapeutics
Nature Reviews Neurology, 2020 The complement system consists of a network of plasma and membrane proteins that modulate tissue homeostasis and contribute to immune surveillance by interacting with the innate and adaptive immune systems.
M. Dalakas, H. Alexopoulos, P. Spaeth
semanticscholar +1 more source
Natural killer cells in the human lung tumor microenvironment display immune inhibitory functions
Journal for ImmunoTherapy of Cancer, 2020 Background Natural killer (NK) cells play a crucial role in tumor immunosurveillance through their cytotoxic effector functions and their capacity to interact with other immune cells to build a coordinated antitumor immune response.
Diane Damotte +20 more
doaj +1 more source
Frontiers in Immunology, 2022 Components of the extracellular matrix (ECM), when exposed to body fluids may promote local complement activation and inflammation. Pathologic complement activation at the glomerular basement membrane and at the Bruch’s membrane is implicated in renal ...
Alexandra Papp +16 more
doaj +1 more source