Results 31 to 40 of about 2,630,357 (343)

A complement to Le Cam's theorem [PDF]

open access: yes, 2007
This paper examines asymptotic equivalence in the sense of Le Cam between density estimation experiments and the accompanying Poisson experiments. The significance of asymptotic equivalence is that all asymptotically optimal statistical procedures can be
Low, Mark G., Zhou, Harrison H.
core   +3 more sources

Unwelcome Complement [PDF]

open access: yesCancer Research, 2009
Abstract For decades, the complement system has been recognized as an effector arm of the innate immunity system that contributes to the destruction of tumor cells. However, recent studies have challenged this paradigm by demonstrating that a complement component, the anaphylatoxin C5a, promotes the growth of malignant tumors in a mouse ...
Maciej M, Markiewski, John D, Lambris
openaire   +2 more sources

Subgraph Complementation [PDF]

open access: yesAlgorithmica, 2020
AbstractA subgraph complement of the graph G is a graph obtained from G by complementing all the edges in one of its induced subgraphs. We study the following algorithmic question: for a given graph G and graph class $${\mathscr {G}}$$G, is there a subgraph complement of G which is in $${\mathscr {G}}$$G?
Fomin, Fedor V.   +3 more
openaire   +3 more sources

Properdin deficiency or anti-properdin treatment ameliorates disease in the C3 gain-of-function mouse model of atypical haemolytic uraemic syndrome

open access: yesFrontiers in Immunology
IntroductionWe have previously shown that the C3D1115N mouse, engineered around a single point mutation in C3 associated with atypical haemolytic uraemic syndrome (aHUS) in man, fully recapitulates the clinical disease. In this study, we investigated the
Grace Mallett   +20 more
doaj   +1 more source

Simple loops on 2-bridge spheres in 2-bridge link complements

open access: yes, 2011
The purpose of this note is to announce complete answers to the following questions. (1) For an essential simple loop on a 2-bridge sphere in a 2-bridge link complement, when is it null-homotopic in the link complement?
Lee, Donghi, Sakuma, Makoto
core   +1 more source

COMPLEMENT-MEDIATED ADIPOCYTE LYSIS BY NEPHRITIC FACTOR SERA [PDF]

open access: yes, 1993
Recent data indicate a previously unsuspected link between the complement system and adipocyte biology. Murine adipocytes produce key components of the alternative pathway of complement and are able to activate this pathway.
Lachmann, PJ   +4 more
core   +1 more source

Altered heme-mediated modulation of dendritic cell function in sickle cell alloimmunization

open access: yesHaematologica, 2016
Transfusions are the main treatment for patients with sickle cell disease. However, alloimmunization remains a major life-threatening complication for these patients, but the mechanism underlying pathogenesis of alloimmunization is not known.
Emmanuelle Godefroy   +7 more
doaj   +1 more source

Natural killer cells in the human lung tumor microenvironment display immune inhibitory functions

open access: yesJournal for ImmunoTherapy of Cancer, 2020
Background Natural killer (NK) cells play a crucial role in tumor immunosurveillance through their cytotoxic effector functions and their capacity to interact with other immune cells to build a coordinated antitumor immune response.
Diane Damotte   +20 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

A homogeneous space whose complement is rigid [PDF]

open access: yes, 2014
We construct a homogeneous subspace of $2^\omega$ whose complement is dense in $2^\omega$ and rigid. Using the same method, assuming Martin's Axiom, we also construct a countable dense homogeneous subspace of $2^\omega$ whose complement is dense in $2 ...
Medini, Andrea   +2 more
core   +1 more source

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