Results 31 to 40 of about 48,485 (265)
As part of the innate immune system, the complement system plays a key role in defense against pathogens and in host cell homeostasis. This enzymatic cascade is rapidly triggered in the presence of activating surfaces.
Anna Duval (12403186) +4 more
core +1 more source
Sequence search and comparative genomic analysis of SUMO-activating enzymes using CoGe
The growing number of genome sequences completed during the last few years has made necessary the development of bioinformatics tools for the easy access and retrieval of sequence data, as well as for downstream comparative genomic analyses.
Lois, L Mariaeditor +3 more
core +2 more sources
As part of the innate immune system, the complement system plays a key role in defense against pathogens and in host cell homeostasis. This enzymatic cascade is rapidly triggered in the presence of activating surfaces.
Anna Duval (12403186) +4 more
core +1 more source
As part of the innate immune system, the complement system plays a key role in defense against pathogens and in host cell homeostasis. This enzymatic cascade is rapidly triggered in the presence of activating surfaces.
Anna Duval (12403186) +4 more
core +1 more source
Protease-Activated Receptor-2 (PAR2) has been implicated through genetic knockout mice with cytokine regulation and arthritis development. Many studies have associated PAR2 with inflammatory conditions (arthritis, airways inflammation, IBD) and key ...
Jacky Y Suen +3 more
doaj +1 more source
C1q/TNF-related protein (CTRP) 6 is a member of the CTRP protein family associated with the regulation of cellular and endocrine processes. CTRP6 contains collagen and globular structures, resembling the pattern recognition molecules (PRMs) of the ...
Krogfelt, Karen Angeliki +3 more
core +1 more source
Gluten degrading enzymes for treatment of celiac disease [PDF]
Celiac disease (CeD) affects about 1% of most world populations. It presents a wide spectrum of clinical manifestations, ranging from minor symptoms to mild or severe malabsorption, and it may be associated with a wide variety of autoimmune diseases. CeD
Darwish, Ghassan M. +9 more
core +1 more source
Structural and computational enzymology: bringing experiments and computations together
In this introductory chapter, we present how the experimental and computational strategies in enzyme research are developed and how they complement each other to provide better insights for understanding enzyme structures and ...
Christo Christov +3 more
core +1 more source
Novel initiator caspase reporters uncover previously unknown features of caspase-activating cells [PDF]
This work was supported by Cancer Research UK (C49979/A17516) and the John Fell Fund, University of Oxford (162/001). L.A.B.-L. is a CRUK Career Development Fellow (C49979/A17516) and an Oriel College, University of Oxford, Hayward Fellow. L.A.
Arthurton, Lewis +12 more
core +1 more source
The alternative or classical pathways for complement system component C3 may be triggered by microorganisms and antigen-antibody complexes. In particular, an activated fragment of C3, C3b, covalently attaches to microorganisms or antigen-antibody ...
Morton, C C; id_orcid +6 more
core +2 more sources

