Results 91 to 100 of about 427,983 (270)
Frontiers in Immunology, 2018 The complement system is an ancient part of the innate immune system important for both tissue homeostasis and host defense. However, bacteria like Staphylococcus aureus (SA) possess elaborative mechanisms for evading both the complement system and other
Anas H. Abu-Humaidan +5 more
doaj +1 more source
MIF as an oncogenic driver of low‐heterogeneity melanomas
Molecular Oncology, EarlyView.Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran +4 more
wiley +1 more source
Involvement of a Complement-Like Factor in the Activation of Blood Protease [PDF]
, 1952 Walton B. Geiger
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Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
arXiv, 2017 $q$-Matroids are defined on complemented modular support lattices. Minors of length 2 are of four types as in a "classical" matroid. Tutte polynomials $\tau(x,y)$ of matroids are calculated either by recursion over deletion/contraction of single elements, by an enumeration of bases with respect to internal/external activities, or by substitution $x \to
arxiv
ACTIVATION OF PROFIBRINOLYSIN BY ANTIGEN-ANTIBODY REACTION AND BY ANAPHYLACTOID AGENTS; ITS RELATION TO COMPLEMENT [PDF]
, 1953 Georges Ungar +2 more
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Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
The explanatory power of activity flow models of brain function [PDF]
arXivTremendous neuroscientific progress has recently been made by mapping brain connectivity, complementing extensive knowledge of task-evoked brain activation patterns. However, despite evidence that they are related, these connectivity and activity lines of research have mostly progressed separately.
arxiv
Studies in Complement Splitting with Special Reference to the Activation of Yeast Absorbed and Complement Deficient Guinea Pig Serum [PDF]
, 1926 Elizabeth I. Parsons
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A potential tumor suppressor role of PLK2 in glioblastoma
FEBS Open Bio, EarlyView.PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia +5 more
wiley +1 more source