Results 41 to 50 of about 277,579 (267)
Human oligodendroglial cells express low levels of C1 inhibitor and membrane cofactor protein mRNAs
Journal of Neuroinflammation, 2004 Background Oligodendrocytes, neurons, astrocytes, microglia, and endothelial cells are capable of synthesizing complement inhibitor proteins. Oligodendrocytes are vulnerable to complement attack, which is particularly observed in multiple sclerosis. This
McGeer Patrick L +2 more
doaj +1 more source
Сахарный диабет, 2011 Aim. Comparative analysis of the levels of the membrane attack complex (MAC) - an end product of complement activation, and of hemolytic activitiesof C1 and C3 complement components in sera of patients with diabetes mellitus 2 (DM2) and healthy subjects.
Elina Alexandrovna Arakelova +5 more
doaj +1 more source
Real frontiers of fake planes [PDF]
, 2015 In [8], we define and partially classify fake real planes, that is, minimal complex surfaces with conjugation whose real locus is diffeomorphic to the euclidean real plane $\mathbb{R}^{2}$.
Dubouloz, Adrien, Mangolte, Frédéric
core +5 more sources
A Novel C1-Esterase Inhibitor Oxygenator Coating Prevents FXII Activation in Human Blood
Biomolecules, 2020 The limited hemocompatibility of currently used oxygenator membranes prevents long-term use of artificial lungs in patients with lung failure. To improve hemocompatibility, we developed a novel covalent C1-esterase inhibitor (C1-INH) coating.
Katharina Gerling +7 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2021 Complement, a feature of the innate immune system that targets pathogens for phagocytic clearance and promotes inflammation, is tightly regulated to prevent damage to host tissue.
Nicholas Peoples, Candace Strang
doaj +1 more source
Angioedema hereditario en Medellín, Colombia: evaluación clínica y de la calidad de vida
Biomédica: revista del Instituto Nacional de Salud, 2015 Introducción. El angioedema hereditario es una inmunodeficiencia primaria de carácter autosómico dominante, debida a un déficit en la proteína inhibidora del factor C1 y caracterizada por episodios recurrentes de edema subcutáneo y de las mucosas.
María Dulfary Sánchez +7 more
doaj +1 more source
Allergy, Asthma & Clinical Immunology, 2021 Background C1 inhibitor (C1-INH) and complement 4 (C4) have historically been referred to as positive acute phase reactants, however this has never been evaluated in hereditary angioedema (HAE) patients.
Peter Stepaniuk +4 more
doaj +1 more source
The correlation between inflammatory biomarkers and polygenic risk score in Alzheimer's Disease [PDF]
, 2017 Plasma biomarkers to aid the early diagnosis of Alzheimer’s disease (AD) or to monitor disease progression have long been sought and continue to be widely studied.
Escott-Price, Valentina +8 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Amniotic fluid embolism pathophysiology suggests the new diagnostic armamentarium: β-tryptase and complement fractions C3-C4 are the indispensable working tools [PDF]
, 2015 Amniotic fluid embolism (AFE) is an uncommon obstetric condition involving pregnant women during labor or in the initial stages after delivery. Its incidence is estimated to be around 5.5 cases per 100,000 deliveries.
Busardo', FRANCESCO PAOLO +3 more
core +2 more sources