Results 11 to 20 of about 42,931 (245)

Echinococcus multilocularis Calreticulin Interferes with C1q-Mediated Complement Activation

Tropical Medicine and Infectious Disease, 2023
As a zoonotic disease caused by Echinococcus multilocularis larvae, alveolar echinococcosis (AE) is one of the most severe forms of parasitic infection. Over a long evolutional process E.
Siqi Xian, Lujuan Chen, Yan Yan, Jianfang Chen, Guixia Yu, Yuxiao Shao, Bin Zhan, Yanhai Wang, Limei Zhao   +8 more
doaj   +3 more sources

Emerging and novel functions of complement protein C1q [PDF]

Frontiers in Immunology, 2015
Complement protein C1q, the recognition subcomponent of the classical pathway, performs a diverse range of complement and non-complement functions. It can bind various ligands derived from self, non-self and altered-self and modulate the functions of ...
Lubna eKouser, Shanmuga Priyaa Madhukaran, Abhishek eShastri, Anuvinder eSaraon, Janez eFerluga, Maha eAl-Mozaini, Uday eKishore   +6 more
doaj   +5 more sources

MafB is a critical regulator of complement component C1q [PDF]

Nature Communications, 2017
The transcription factor MafB is expressed by monocytes and macrophages. Efferocytosis (apoptotic cell uptake) by macrophages is important for inhibiting the development of autoimmune diseases, and is greatly reduced in Mafb-deficient macrophages.
Andrea Christina-Sylvia, Asano Keigo, Fujii Risa, Hamada Michito, Hattori Motochika, Imamura Yuki, Jeon Hyojung, Kamei Risa, Kobayashi Makoto, Koshida Ryusuke, Kudo Takashi, Kulathunga Kaushalya, Matsunaga Yurina, Nakamura Megumi, Oishi Hisashi, Shiraishi Risako, Takahashi Satoru, Tran Mai Thi Nhu, Tsunakawa Yuki, Usui Toshiaki, 小林 麻己人, 工藤 崇, 濱田 理人, 越田 隆介, 高橋 智   +24 more
core   +5 more sources

Complement C1q induces the M2-polarization of tumor-associated macrophages in lung adenocarcinoma. [PDF]

Genes Dis, 2023
Song Y, Fu Y, Wang J, Tang J, Yin J, Zhang Z, Song Q, Zhang B.   +7 more
europepmc   +2 more sources

Prognostic Implications of the Complement Protein C1q in Gliomas [PDF]

Frontiers in Immunology, 2019
The contribution of the complement system in the pathophysiology of brain cancers has been recently considered in light of its well-known involvement in carcinogenesis.
Alessandro Mangogna, Beatrice Belmonte, Chiara Agostinis, Paola Zacchi, Domenico Gerardo Iacopino, Anna Martorana, Vito Rodolico, Deborah Bonazza, Fabrizio Zanconati, Uday Kishore, Roberta Bulla   +10 more
doaj   +6 more sources

Serum Level of Complement C1q is Associated with Contrast-Associated Acute Kidney Injury in Patients Undergoing Emergency Percutaneous Coronary Intervention. [PDF]

J Inflamm Res, 2021
Tao J, Ye C, Dai W, Li D, Zhou M, Li Y.
europepmc   +3 more sources

Autoantibodies against complement component C1q in systemic lupus erythematosus [PDF]

Clinical & Translational Immunology, 2021
Systemic lupus erythematosus (SLE) is the archetype of a systemic autoimmune disease, but the multifaceted pathogenic mechanisms leading to inflammation and organ damage are not fully understood.
Marten Trendelenburg
doaj   +3 more sources

Complement C1q and von Willebrand factor interaction in atherosclerosis of human carotid artery. [PDF]

Front Immunol, 2023
Schulz K, Donat C, Punjabi M, Glatz K, Kaufmann B, Trendelenburg M.   +5 more
europepmc   +3 more sources

Epigenetic regulation of complement C1Q gene expression. [PDF]

Front Immunol
Human C1q is a multifaceted complement protein whose functions range from activating the complement classical pathway to immunomodulation and promoting placental development and tumorigenesis. It is encoded by the C1QA, C1QB, and C1QC genes located on chromosome 1.
Pegoraro S, Balduit A, Mangogna A, Kishore U, Ricci G, Agostinis C, Bulla R.   +6 more
europepmc   +6 more sources

Complement C1q in plasma induces nonspecific binding of poly(acrylic acid)-coated upconverting nanoparticle antibody conjugates. [PDF]

Anal Bioanal Chem, 2022
Kuusinen S, Ekman M, Raiko K, Hannula H, Lyytikäinen A, Lahtinen S, Soukka T.   +6 more
europepmc   +3 more sources