Binding of complement subcomponent C1q to Streptococcus pyogenes: evidence for interactions with the M5 and FcRA76 proteins [PDF]
, 2006 I. V. Koroleva +2 more
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TREM2‐Mediated Myeloid Cells Protect Against Pathological Choroidal Neovascularization
The FASEB Journal, Volume 39, Issue 14, 31 July 2025.This study demonstrates that TREM2 is selectively upregulated in activated microglia and macrophages during choroidal neovascularization (CNV). Single‐cell RNA sequencing and immunostaining confirmed its enrichment in IBA1+ myeloid cells near CNV lesions. Functionally, TREM2 haploinsufficiency worsened CNV lesion size and vascular leakage.
Tianxi Wang +5 more
wiley +1 more source
C1q, the recognition subcomponent of the classical pathway of complement, drives microglial activation [PDF]
, 2008 Katrin Färber +6 more
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Elevated Plasma Complement C1q Levels Contribute to a Poor Prognosis After Acute Primary Intracerebral Hemorrhage: A Prospective Cohort Study. [PDF]
Front Immunol, 2022 Wang Z +10 more
europepmc +1 more source
Highly specific inhibition of C1q globular-head binding to human IgG: A novel approach to control and regulate the classical complement pathway using an engineered single chain antibody variable fragment [PDF]
, 2008 Hee Hwang +3 more
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Complement C1q in plasma induces nonspecific binding of poly(acrylic acid)-coated upconverting nanoparticle antibody conjugates. [PDF]
Anal Bioanal Chem, 2022 Kuusinen S +6 more
europepmc +1 more source
Elevated Serum Complement C1q Levels After Traumatic Brain Injury and Its Association with Poor Prognosis. [PDF]
Neuropsychiatr Dis Treat, 2022 Yan XJ, Li YB, Liu W, Wu HY, Yu GF.
europepmc +1 more source
Complement Protein C1q Forms a Complex with Cytotoxic Prion Protein Oligomers [PDF]
, 2010 Paul Erlich +8 more
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