Results 21 to 30 of about 41,476 (260)
C1q and phagocytosis: the perfect complement to a good meal [PDF]
Journal of Leukocyte Biology, 2012 Abstract Review on the role for C1q in enhancement of phagocytosis, specifically focusing on C1q-mediated clearance of apoptotic cells. Complement component C1q is a member of a family of soluble proteins called defense collagens, which are important in host defense and apoptotic cell clearance.
Manuel Galvan +2 more
openalex +5 more sources
Echinococcus multilocularis Calreticulin Interferes with C1q-Mediated Complement Activation
Tropical Medicine and Infectious Disease, 2023 As a zoonotic disease caused by Echinococcus multilocularis larvae, alveolar echinococcosis (AE) is one of the most severe forms of parasitic infection. Over a long evolutional process E.
Siqi Xian +8 more
doaj +1 more source
Hepatology, EarlyView., 2022 Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong +9 more
wiley +1 more source
Transcriptional factor PU.1 regulates decidual C1q expression in early pregnancy in human [PDF]
, 2015 "Copyright: © 2015 Madhukaran, Kishore, Jamil, Teo, Choolani and Lu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Choolani, M +5 more
core +5 more sources
Complement in Renal Disease as a Potential Contributor to Arterial Hypertension
Kidney & Blood Pressure Research, 2021 Objective: Complement deposition is prevalent in kidney biopsies of patients with arterial hypertension and hypertensive nephropathy, but an association of hypertension and complement deposition or involvement of complement in the pathogenesis of ...
Lisa-Maren Fischer +6 more
doaj +1 more source
The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies. [PDF]
, 2016 Central to the humoral theory of transplantation is production of antibodies by the recipient against mismatched HLA antigens in the donor organ. Not all mismatches result in antibody production, however, and not all antibodies are pathogenic.
Farber, John, Filippone, Edward J
core +8 more sources
Complement Component C1q and Anti‐C1q Antibodies in Theory and in Clinical Practice [PDF]
Scandinavian Journal of Immunology, 2008 AbstractThe complement system is a major part of the innate immunity. The first component of the classical pathway of complement activation, C1q, plays a crucial role in the clearance of immune complexes and apoptotic bodies from the organism. Autoantibodies against C1q (anti‐C1q) have been found in a number of autoimmune and infectious diseases.
P. Kralikova, E. Potlukova
openaire +3 more sources
Frontiers in Immunology, 2020 To investigate the fine epitope(s) of anti-C1q A08 antibodies and their roles in complement activation in lupus nephritis, C1q A08 and related peptides with various amino acid sequences around A08 were synthesized.
Wen-Jun Wu +23 more
doaj +1 more source
C1q-targeted inhibition of the classical complement pathway prevents injury in a novel mouse model of acute motor axonal neuropathy [PDF]
, 2016 Introduction Guillain-Barré syndrome (GBS) is an autoimmune disease that results in acute paralysis through inflammatory attack on peripheral nerves, and currently has limited, non-specific treatment options.
Barrie, Jennifer A. +8 more
core +2 more sources
Frontiers in Aging Neuroscience, 2022 BackgroundThe immune response and the complement system are associated with cognitive impairment and diabetes mellitus, respectively. Activation of the complement system in these diseases occurs mainly through either the classical pathway or the ...
Zhenxing Li +7 more
doaj +1 more source