Results 171 to 180 of about 796,318 (197)

Non-coordinated biosynthesis of early complement components in a deficiency of complement proteins C1r and C1s.

Scandinavian journal of immunology, 1994
We report on a 60-year-old woman with systemic lupus erythematosus and a total (95%) C1r and a partial (36%) C1s deficiency. The patient complained about cutaneous lesions on forearms and legs without other systemic involvement. Elevated anti-nuclear, anti-native DNA and anti-SSA antibodies were present.
A, Chevailler, C, Drouet, D, Ponard, C, Alibeu, S, Suraniti, F, Carrère, G, Renier, D, Hurez, M G, Colomb   +8 more
openaire   +1 more source

Tandem Mass Tag-Labeled Quantitative Proteome Analyses Identify C1R and A2M as Novel Serum Biomarkers in Pregnant Women with Obstructive Sleep Apnea.

Journal of Proteome Research
The aim of this study was to identify serum diagnostic biomarkers associated with the severity of obstructive sleep apnea (OSA) during pregnancy. Differentially expressed proteins (DEPs) were identified in the control (C), mild (O), and moderate (MO) OSA
Qiang Zhang, Y. Yue, Xueqing Wang, Hong Cui, Yishu Liu, Man Gao, Tong Liu, Li Xiao   +7 more
semanticscholar   +1 more source

Ca(2+)-linked association of human complement C1s and C1r.

Biochemistry, 1994
The weight-average molecular weight of Clr, an activated serine protease subcomponent of complement Cl, was measured in the presence of widely varying concentrations of Ca2+ and the other serine protease subcomponent, Cls, by utilizing the technique of tracer sedimentation equilibrium.
G, Rivas, K C, Ingham, A P, Minton
openaire   +1 more source

A polymorphism detected in sheep using a complement subcomponent C1r (C1R) probe

Journal of Animal Science, 1995
S H, Phua, N J, Wood
openaire   +2 more sources

Guianensin, a blackfly salivary protein, inhibits the lectin pathway of complement 9038

Journal of Immunology
Salivary secretions from blood feeding arthropods are rich in bioactive compounds that counteract blood clotting, platelet aggregation, complement activation, and vasoconstriction. Despite the identification and characterization of various salivary
Paola Carolina Valenzuela, Molly Ring, Erika Sayuri, Nishiduka Costa, Brian Bonilla, Phillip Cruz, Eric Calvo   +6 more
semanticscholar   +1 more source

A common amino acid polymorphism in complement component C1R

Human Molecular Genetics, 1994
M M, Nöthen, G, Dewald
openaire   +2 more sources

Autocatalytic activation of C1r subcomponent of the first component of human complement.

Journal of biochemistry, 1985
Autoactivation of the proenzyme form of a subunit of the first component (C1r) was performed in the presence and absence of diisopropyl fluorophosphate (DFP). The time-course of autoactivation of zymogen C1r followed a sigmoidal curve and was accelerated by addition of the enzyme C1r and by increasing the concentration of C1r, suggesting that ...
Y, Kasahara, H, Odai, K, Takahashi, S, Nagasawa, J, Koyama   +4 more
openaire   +1 more source

The substrate specificity of the complement initiating protease, C1r

Molecular Immunology, 2010
Lakshmi C. Wijeyewickrema, Thuy Tran, Phillip E. Thompson, Anthony Matthews, Dion Kaiserman, Phillip Bird, Robert Pike   +6 more
openaire   +1 more source

Familial deficiency of two subunits of the first component of complement. C1r and C1s associated with a lupus erythematosus-like disease.

Arthritis & Rheumatism, 1978
Stanley L. Lee, Stanley L. Wallace, Richard Barone, Richard Barone, Livia Blum, P. Chase   +5 more
semanticscholar   +1 more source

Human complement C1r and C1s proteins and genes: studies with molecular probes.

Behring Institute Mitteilungen, 1989
The isolation of complementary DNA clones for both enzymic subcomponents of C1 has made it possible to derive their complete amino acid sequences and to verify and extend previous protein data. We review here recent advances in studies of the C1r and C1s proteins and of the corresponding genes, using molecular probes.
M, Tosi, A, Journet, C, Duponchel, E, Couture-Tosi, T, Meo   +4 more
openaire   +1 more source