Results 111 to 120 of about 27,085 (217)

Mapping of the Epstein-Barr virus and C3dg binding sites to a common domain on complement receptor type 2. [PDF]

, 1989
Complement receptor type 2 (CR2;CD21), a member of the superfamily of proteins containing short consensus repeats (SCRs), is the B cell receptor for both the gp350/220 envelope protein of Epstein-Barr virus (EBV), and for the C3dg protein of complement ...
Ahearn, JM, Carter, RH, Fearon, DT, Klickstein, LB, Lowell, CA, Mitchell, JA   +5 more
core  

Pattern of degradation of human complement fragment, C3b [PDF]

FEBS Letters, 1981
Sim, Edith, Wood, Andrew B., Hsiung, Li-Min, Sim, Robert B.   +3 more
openaire   +2 more sources

Enhanced expression of human monocyte complement (C3b) receptors by chemoattractants. [PDF]

Clinical and experimental immunology, 1980
The capacity of various leucoattractants to enhance, or unfold, receptors for complement (C3b) on human blood monocytes has been studied. A number of recognized monocyte chemoattractants including casein, supernatants from C. parvum 10390 and from human lymphocytes (cultured either in the presence or absence of phytohaemagglutinin) and the formyl ...
GLASS, EJ, KAY, AB
openaire   +1 more source

Factor H interferes with the adhesion of sickle red cells to vascular endothelium: a novel disease-modulating molecule

Haematologica, 2019
Sickle cell disease is an autosomal recessive genetic red cell disorder with a worldwide distribution. Growing evidence suggests a possible involvement of complement activation in the severity of clinical complications of sickle cell disease.
Elisabetta Lombardi, Alessandro Matte, Antonio M. Risitano, Daniel Ricklin, John D. Lambris, Denise De Zanet, Sakari T. Jokiranta, Nicola Martinelli, Cinzia Scambi, Gianluca Salvagno, Zeno Bisoffi, Chiara Colato, Angela Siciliano, Oscar Bortolami, Mario Mazzuccato, Francesco Zorzi, Luigi De Marco, Lucia De Franceschi   +17 more
doaj   +1 more source

Biofilm Formation Induces C3a Release and Protects Staphylococcus epidermidis from IgG and Complement Deposition and from Neutrophil-Dependent Killing [PDF]

, 2017
BackgroundBiofilm formation is considered to be an important virulence factor of the opportunistic pathogen Staphylococcus epidermidis. We hypothesized that biofilm formation could interfere with the deposition of immunoglobulins and complement on the ...
Birkenstock, Timo A., Götz, Friedrich, Kristian, Sascha A., Landmann, Regine, Mack, Dietrich, Sauder, Ursula   +5 more
core  

Immune evasion of Borrelia miyamotoi: CbiA, a novel outer surface protein exhibiting complement binding and inactivating properties

Scientific Reports, 2017
Borrelia (B.) miyamotoi, an emerging tick-borne relapsing fever spirochete, resists complement-mediated killing. To decipher the molecular principles of immune evasion, we sought to identify determinants contributing to complement resistance.
Florian Röttgerding, Alex Wagemakers, Joris Koetsveld, Volker Fingerle, Michael Kirschfink, Joppe W. Hovius, Peter F. Zipfel, Reinhard Wallich, Peter Kraiczy   +8 more
doaj   +1 more source

CG001, a C3b-targeted complement inhibitor, blocks 3 complement pathways: development and preclinical evaluation

Blood Advances
Abstract Excessively activated or dysregulated complement activation may contribute to the pathogenesis of a wide range of human diseases, thus leading to a surge in complement inhibitors. Herein, we developed a human-derived and antibody-like C3b-targeted fusion protein (CRIg-FH-Fc) x2, termed CG001, that could ...
Ling Li, Peipei Ding, Yanrong Dong, Shupei Shen, Xinyue Lv, Jie Yu, Luying Li, Jianfeng Chen, Pilin Wang, Bing Han, Ting Xu, Weiguo Hu   +11 more
openaire   +2 more sources

Serum amyloid P aids complement-mediated immunity to Streptococcus pneumoniae [PDF]

, 2007
The physiological functions of the acute phase protein serum amyloid P (SAP) component are not well defined, although they are likely to be important, as no natural state of SAP deficiency has been reported.
Botto, M., Bottoms, S.E., Brown, J.S., Yuste, J.   +3 more
core  

The role of hypoxia and complement receptor 2 or toll-like receptor 2 on B1 B cell effector function [PDF]

Master of ScienceDivision of BiologySherry D. FlemingProfessional phagocytes play a critical role in maintaining homeostasis within a host through phagocytic, microbicidal, and inflammatory activity.
Knights, Kaori
core   +1 more source

A Khintchine type theorem for hyperplanes

, 2005
We prove that the convergence Khintchine theorem holds for affine hyperplanes whose parametrizing matrices satisfy a mild Diophantine condition.
Ghosh, Anish
core   +1 more source