Results 151 to 160 of about 3,342 (187)

Generation of a C3c specific monoclonal antibody and assessment of C3c as a putative inflammatory marker derived from complement factor C3

Journal of Immunological Methods, 2010
There is a general need for markers of systemic inflammation in acute or chronic diseases, where complement activation is involved. Available methods to monitor complement activation are elaborate and of low sensitivity; they include haemolytic assays (CH50), quantification of fluid phase terminal complex (C5b-C9) and quantification of complement split
Yaseelan Palarasah, Karsten Skjodt, B Teisner   +2 more
exaly   +6 more sources

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Circulating complement (C3),C3c and immune complexes in ABPA patients

Serodiagnosis and Immunotherapy in Infectious Disease, 1990
Abstract Complement (C3), its split product (C3c), CRP and circulating immune complexes were studied in 10 patients with allergic bronchopulmonary aspergillosis (ABPA) and compared with 10 age and sex matched controls. An insignificant decrease and significant increase in the levels of C3 and C3c, respectively, was observed in ABPA patients in ...
Banani Banerjee
exaly   +2 more sources

A single step immunoelectrophoresis method for the quantitation of complement C3c in biological fluids

Journal of Immunological Methods, 1983
An intermediate gel rocket immunoelectrophoresis (IRI) suitable for direct quantitation of complement split products with C3c specificity is described. The technique represents a simple, quick, and reproducible method for the assessment of complement activity in biological fluids in diseases.
Henning Sørensen
exaly   +3 more sources

Hypercatabolism of Complement in Crohn's Disease—Assessment of Circulating C3c

Acta Medica Scandinavica, 1983
ABSTRACT. Split products from the main complement component 3 (C3) were investigated in untreated outpatients, 20 with Crohn's disease and 20 with ulcerative colitis. The median plasma concentration of c split product of C3 (C3c) in normals was 2 mg·l‐1, in patients with Crohn's disease 20 mg·l‐1 and in patients with ulcerative colitis 3 mg·l‐1.
J Elmgreen, Henning Sørensen
exaly   +3 more sources

Complement C3c and related protein biomarkers in amyotrophic lateral sclerosis and Parkinson’s disease

Biochemical and Biophysical Research Communications, 2006
We have used quantitative 2D gel electrophoresis to analyze serum proteins from 422 patients with neurodegenerative diseases and normal individuals in an unbiased approach to identify biomarkers. Differences in abnormal serum levels were found between amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), and related disorders for 34 protein ...
Ira L Goldknopf, Albert A Yen, Stanley H Appel   +2 more
exaly   +3 more sources

Isolation of the porcine complement activation fragments C3c and C3d and their use in the preparation of monospecific antibodies

Veterinary Immunology and Immunopathology, 1993
The hemolytic test to date has been the sole analytic technique applied to study the complement reaction in the swine. To improve the analytical possibilities for this species we have developed polyclonal antibody reagents with specificities for the C3c and C3d activation fragments of swine C3. Access to these reagents, by which activation products can
U R Nilsson
exaly   +3 more sources

Levels of complement components iC3b, C3c, C4, and SC5b-9 in peritoneal fluid and serum of infertile women with endometriosis

Fertility and Sterility, 2007
To assess whether complement components iC3b, C3c, C4, and SC5b-9 may be involved in the pathogenesis of endometriosis.Prospective, experimental trial.Medical university.112 women infertile women undergoing laparoscopy.Venipuncture and laparoscopic peritoneal fluid collection.Peritoneal fluid and serum iC3b, C3c, C4, and SC5b-9 levels were measured by ...
Justyna Sikora, Aleksandra Mielczarek-Palacz   +1 more
exaly   +3 more sources

Activation and fragmentation of the third (C3) and the fourth (C4) components of complement: Generation and isolation of physiologically relevant fragments C3c and C4c

Journal of Immunological Methods, 1985
The degree of the activation and fragmentation of C4 and C3, including chain structure of the activation products, was evaluated by SDS-PAGE analysis of the C4 or C3 antigens that were withdrawn from the reaction media with appropriate immunoadsorbent beads.
J Janatova
exaly   +3 more sources

Levels of Complement Receptor Type One (CR1, CD35) on Erythrocytes, Circulating Immune Complexes and Complement C3 Split Products C3d and C3c Are Not Changed by Short-Term Physical Exercise or Training

International Journal of Sports Medicine, 1992
The effect of heavy short-term physical exercise on the levels of complement receptor type one (CR1, CD35) on erythrocytes, the concentrations of circulating immune complexes (IC), and the complement C3 split products C3c and C3d were examined in young healthy males.
B S Thomsen, Bente Klarlund Pedersen
exaly   +3 more sources

High levels of C3c in the cerebrospinal fluid from amyotrophic lateral sclerosis patients

Acta Neurologica Scandinavica, 1985
A study of several parameters of the humoral immunity in the serum and the cerebrospinal fluid (CSF) of thirteen Amyotrophic Lateral Sclerosis (ALS) patients was carried out. A significant increase in CSF C3c was shown.
Pasquale Annunziata, N Volpi
exaly   +2 more sources