Results 81 to 90 of about 3,342 (187)

A study of detection and comparison of immunofluorescence on formalin-fixed paraffin-embedded tissue with fresh frozen renal biopsy specimen

Saudi Journal of Kidney Diseases and Transplantation, 2019
Direct immunofluorescence on the fresh frozen tissue is established way of demonstrating of immunoglobulins and complement deposition in renal biopsies. IF studies can be done on paraffin-fixed tissue (IF-P) and give comparable results to those obtained ...
Ranjana Solanki, Madan Kumar Solanki, Deepika Hemrajani, Jayesh Saha   +3 more
doaj   +1 more source

Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy

Frontiers in Immunology, 2018
Membranous nephropathy is an immune kidney disease caused by IgG antibodies that form glomerular subepithelial immune complexes. Proteinuria is mediated by complement activation, as a result of podocyte injury by C5b-9, but the role of specific ...
Wentian Luo, Wentian Luo, Florina Olaru, Florina Olaru, Jeffrey H. Miner, Laurence H. Beck, Johan van der Vlag, Joshua M. Thurman, Dorin-Bogdan Borza, Dorin-Bogdan Borza   +9 more
doaj   +1 more source

Komplemen Serum C3c dan Limfosit T-CD4+ Darah

, 2013
The incidence of HIV and AIDS infection continues to increase despite various treatments have been applied, thus the mortality rate remains high. The examination of CD4+ T lymphocytes number to determine the immune status and the monitoring of therapy ...
Parwati, I Komang, Agustina Tambunan, Betty, Retnowati, Endang   +2 more
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A comparative proteomic study of sera in paediatric systemic lupus erythematosus patients and in healthy controls using MALDI-TOF-TOF and LC MS–A pilot study

Pediatric Rheumatology Online Journal, 2012
Background Paediatric systemic lupus erythematosus (pSLE) exhibits an aggressive clinical phenotype with severe complications and overall poor prognosis.
Rana Anita, Minz Ranjana W, Aggarwal Ritu, Sharma Sadhna, Pasricha Neelam, Anand Shashi, Singh Surjit   +6 more
doaj   +1 more source

The Effect of surgical operation on the levels of plasma fibronectin, immunoglobulins IgG, IgM, IgA and complement factor C3c

, 1990
Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır. Yayınlanma izni olmayan tezlerin basılı kopyalarına Üniversite kütüphaneniz aracılığıyla (TÜBESS üzerinden) erişebilirsiniz.Sağlık Bilimleri Enstitüsü, Mikrobiyoloji Ana Bilim DalıÖZET 1989
Ünlü, Mehmet
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Complement Factor H: solution structures and interactions with ligands

, 2009
Factor H (FH) is a plasma glycoprotein that plays a central role in regulating the alternative pathway of complement. It is composed of 20 short complement regulator (SCR) domains.
Okemefuna, A.I.
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Complement activation products in the circulation and urine of primary membranous nephropathy

BMC Nephrology, 2019
Background Complement activation plays a substantial role in the pathogenesis of primary membranous nephropathy (pMN). C5b-9, C3c, MBL, and factor B have been documented in the subepithelial immune deposits. However, the changing of complement activation
Mu-fan Zhang, Jing Huang, Yi-miao Zhang, Zhen Qu, Xin Wang, Fang Wang, Li-qiang Meng, Xu-yang Cheng, Zhao Cui, Gang Liu, Ming-hui Zhao   +10 more
doaj   +1 more source

Ultrastr uctural study of the undulated epithelial side of glomer ular basement membrane in membranousnephropathy；clinicopathological study of 20 patients [PDF]

, 2015
Introduction: Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults and is characterized by electron-dense deposits (EDD) in the glomerular basement membrane (GBM).
Yoshimoto, Taichiro, Suzuki, Tsukasa, Maeda, Masayuki, Fukushima1, Noriyoshi   +3 more
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Platelets are activated in ANCA-associated vasculitis via thrombin-PARs pathway and can activate the alternative complement pathway

Arthritis Research & Therapy, 2017
Background In this study, we investigated the mechanism of platelet activation in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), as well as the activation of the alternative complement pathway by platelets in AAV ...
Di Miao, Dan-Yang Li, Min Chen, Ming-Hui Zhao   +3 more
doaj   +1 more source

Complement activation in amyloid plaques in Alzheimer's dementia

, 1988
Amyloid plaques in Alzheimer's dementia contain complement factors C1q, C4 and C3. In the present study we demonstrate complement activation in amyloid plaques using immunoenzymatical techniques and specific antibodies against subunits of individual ...
Eikelenboom, P., Hack, C. E., Rozemuller, J. M., Stam, F. C.   +3 more
core   +1 more source