Results 61 to 70 of about 3,342 (187)

Circulating C3, C4, and C3 Split Products (C3c and C3d) During Normal Pregnancy

, 1982
: The plasma concentrations of the complement components C3 and C4, as well as the split products C3c and C3d, were measured before, during, and after normal pregnancy.
TEISNER, BORGE, LAHOOD, JAMES, TUCKER, MALCOLM, GRUDZINSKAS, JURGIS G., HAU, JANN   +4 more
core   +1 more source

Implementation Punctuation: The Role of Feedback, Narratives, and Implementation in the Punctuated Equilibrium Theory

Policy Studies Journal, Volume 54, Issue 2, May 2026.
ABSTRACT Based on the Punctuated Equilibrium Theory (PET) and implementation research, this study proposes an extended conceptualization of policy punctuation that enables researchers to systematically include policy implementation as part of a punctuation. The key mechanisms underlying the PET, i.e., policy image and venue, information processing, and
Bettina Stauffer
wiley   +1 more source

Complement activation in experimental and human temporal lobe epilepsy

Neurobiology of Disease, 2007
We investigated the involvement of the complement cascade during epileptogenesis in a rat model of temporal lobe epilepsy (TLE), and in the chronic epileptic phase in both experimental as well as human TLE.
E. Aronica, K. Boer, E.A. van Vliet, S. Redeker, J.C. Baayen, W.G.M. Spliet, P.C. van Rijen, D. Troost, F.H. Lopes da Silva, W.J. Wadman, J.A. Gorter   +10 more
doaj   +1 more source

Yi Shen An, a Chinese traditional prescription, ameliorates membranous glomerulonephritis induced by cationic bovine serum albumin in rats

Pharmaceutical Biology, 2022
Context Yi Shen An (YSA) is an investigational composite of traditional Chinese medicine (Reference: 2010L000974) for the treatment of renal disease.
Yun-Li Zhao, Xiang-Hua Zhang, Feng Guo, Ying Wei, Jian-Hua Shang, Xiao-Dong Luo   +5 more
doaj   +1 more source

Noninvasive Monitoring of Complement Using the Bioluminescent Modified Ham Assay in the Second Porcine‐to‐Human Live Heart Transplant

Xenotransplantation, Volume 33, Issue 3, May/June 2026.
ABSTRACT Complement activation is a major barrier to xenotransplantation. We report detailed complement monitoring in a 58‐year‐old man who received a 10 gene–edited porcine heart expressing human complement regulators CD46 and CD55. Despite these transgenes and prophylactic systemic complement inhibition with C1 esterase inhibitor (C1INH), early ...
Michael A. Cole, Andy Tully, Javier Galindo, Avneesh K. Singh, Meryl Waldman, Janhavi Athale, Idris Boudhabhay, Erwan Morgand, Fariza Mezine, Valentin Goutaudier, Aurélie Sannier, Brad Lewis, Jamey Kain, Mike Ero, Lubka Roumenina, Patrick Bruneval, Robert Christenson, Lo Tamburro, Alan Burke, Cinthia Drachenburg, Alexandre Loupy, David Ayares, Robert A. Brodsky, Bartley P. Griffith, Muhammad M. Mohiuddin, Alison Grazioli   +25 more
wiley   +1 more source

Yersinia enterocolitica O:3 Outer Membrane Vesicles as a Platform for Complement Activation

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
Basic characteristics and biological activity of outer membrane vesicles (OMVs) secreted by Yersinia enterocolitica O:3 (YeO3), depending on LPS chemotype and growth temperature. ABSTRACT Lipopolysaccharide (LPS) is the major component of the outer membrane vesicles (OMVs) of Gram‐negative bacteria.
Cédric Battaglino, Iryna Bodnaruk, Paula Czyszczoń, Mikael Skurnik, Beata Filip‐Psurska, Dariusz Jarych, Anna Maciejewska, Mariusz Gadzinowski, Kamil Malik, Izabela Potocka, Paweł Migdał, Roksana Kruszakin, Maciej Cedzyński, Katarzyna Kasperkiewicz, Jolanta Lukasiewicz, Anna S. Świerzko   +15 more
wiley   +1 more source

Immune complexes and complement in serum and synovial fluid of rheumatoid arthritis patients [PDF]

Journal of Medical Biochemistry, 2009
Rheumatoid arthritis (RA) is predominantly an intraarticular inflammatory and autoimmune disease that involves different autoantibodies and effector mechanisms.
Mijušković Zoran, Rackov Ljiljana, Pejović Janko, Živanović Sandra, Stojanović Jelica, Kovačević Zoran   +5 more
doaj  

Dysregulation of Extracellular Vesicle Concentration, MicroRNAs, and Surface Proteins in Patients With Niemann‐Pick Disease Type C

Journal of Extracellular Biology, Volume 5, Issue 4, April 2026.
ABSTRACT Niemann‐Pick disease type C (NPC) is a rare neurodegenerative disease primarily caused by mutations in the NPC1 gene, which is associated with cholesterol trafficking impairment, and disruption of endolysosomal processing and extracellular vesicles (EVs).
Sarah Catherine BB Hawthorne, Ursula S Sandau, Trevor J McFarland, Elizabeth Berry‐Kravis, Julie A Saugstad   +4 more
wiley   +1 more source

Glomerular Complement Factor H–Related Protein 5 (FHR5) Is Highly Prevalent in C3 Glomerulopathy and Associated With Renal Impairment

Kidney International Reports, 2019
Introduction: Therapeutic agents that target complement are increasingly available for glomerular diseases. However, the mechanisms linking glomerular complement deposition with inflammation and damage are incompletely understood.
Nicholas R. Medjeral-Thomas, Hilary Moffitt, Hannah J. Lomax-Browne, Nicholas Constantinou, Tom Cairns, H. Terence Cook, Matthew C. Pickering   +6 more
doaj   +1 more source

Machine Learning Model for an App‐Based Tool to Assist With the Diagnosis of Canine Atopic Dermatitis

Veterinary Dermatology, Volume 37, Issue 2, Page 236-246, April 2026.
Canine atopic dermatitis (cAD) is a chronic condition requiring life‐long management. Accurate diagnosis can be challenging, with no reliable diagnostic test. This study aimed to generate a simple diagnostic model for cAD. This model is a relevant prototype for an app‐based tool to support general practitioners in the diagnosis of cAD alongside ...
Xavier Langon, Mathieu Montoya, Isabelle Gourdon   +2 more
wiley   +1 more source