Results 61 to 70 of about 3,130 (159)

Tolerability and Feasibility of Minimally Invasive Canine Skin Sampling: Excellent Tolerability Meets Transcriptomic Challenges

Veterinary Dermatology, Volume 37, Issue 3, Page 375-385, June 2026.
ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann, Lisa B. Mamo, Allison N. Dickey   +2 more
wiley   +1 more source

Glomerular Complement Factor H–Related Protein 5 (FHR5) Is Highly Prevalent in C3 Glomerulopathy and Associated With Renal Impairment

Kidney International Reports, 2019
Introduction: Therapeutic agents that target complement are increasingly available for glomerular diseases. However, the mechanisms linking glomerular complement deposition with inflammation and damage are incompletely understood.
Nicholas R. Medjeral-Thomas, Hilary Moffitt, Hannah J. Lomax-Browne, Nicholas Constantinou, Tom Cairns, H. Terence Cook, Matthew C. Pickering   +6 more
doaj   +1 more source

Microscopic Polyangiitis After Pulmonary Nontuberculous Mycobacterial Disease: A Case Report and Literature Review

Respirology Case Reports, Volume 14, Issue 5, May 2026.
This case highlights that ANCA‐associated vasculitis can emerge in patients with chronic airway disease and a history of nontuberculous mycobacterial infection, potentially masquerading as infection‐related inflammation. Early recognition based on extrapulmonary clues (urinary abnormalities and neuropathy) enabled prompt diagnosis and treatment with ...
Hidenori Takahashi, Riho Nakagawa, Mio Toyama‐Kousaka, Yugo Satake, Hiroki Nagamatsu, Ryutaro Hirose, Naoya Toba, Shinichiro Ota, Miwa Morikawa, Natsuko Nakano, Kazuyoshi Ishigaki, Masaharu Shinkai   +11 more
wiley   +1 more source

The therapeutic effects of Jaceosidin on lipopolysaccharide-induced acute lung injury in mice

Journal of Pharmacological Sciences, 2019
Acute lung injury (ALI) results from various factors including uncontrolled pulmonary inflammation, oxidative damage and the over-activated complement with high mortality rates.
Xiao-lei Huang, Xiao-chen Wei, Leng-qiu Guo, Lei Zhao, Xi-hua Chen, Ya-dong Cui, Jie Yuan, Dao-feng Chen, Jian Zhang   +8 more
doaj   +1 more source

Unraveling the Mystery of Melt Migration in Migmatites: From Channeling Instability to Pattern Formation

Journal of Geophysical Research: Solid Earth, Volume 131, Issue 5, May 2026.
Abstract Melt migration in partially molten rocks is commonly described by porous flow models controlled by the hydro‐mechanical compaction length, which effectively explains melt extraction at mid‐ocean ridges. However, this framework cannot account for the paradoxical accumulation of small melt fractions into rhythmic leucosome–melanosome bands in ...
Qingpei Sun, Manman Hu, Roberto Weinberg, Klaus Regenauer‐Lieb   +3 more
wiley   +1 more source

Mannose-binding lectin deficiency with eosinophilic meningoencephalitis due to Angiostrongylus cantonensis in children: a case series

Journal of Medical Case Reports, 2011
Introduction Eosinophilic meningitis, a potentially fatal disease caused by Angiostrongylus cantonensis, is considered an emerging infectious disease.
de Paula-Almeida Olga, Martínez-Alderete René H, Bu-Coifiu-Fanego Raisa, Dorta-Contreras Alberto J, Padilla-Docal Bárbara, Reiber Hansotto, Jensenius Jens   +6 more
doaj   +1 more source

Investigation of Potential Risks in Bio‐Based Food Contact Materials (FCMs) From Microbial Exploitation of Agricultural Wastes: Case Studies of Bacterial Cellulose and Nisin

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT In the context of the circular economy and the increasing demand for safe and sustainable packaging, this work addresses the safety assessment of food contact materials (FCMs) derived from agro‐industrial by‐products. Despite growing interest in these bio‐based materials, the literature still lacks a structured safety‐assessment framework able
Marianna Ciccone, Emmanouil Tsochatzis, Joel Armando Njieukam, Lorenzo Siroli, Davide Gottardi, Rosalba Lanciotti, Francesca Patrignani   +6 more
wiley   +1 more source

Direct Immunofluorescence and Immunohistochemistry in Diagnostics of Glomerulonephritis

Biomolecules & Biomedicine, 2008
The needle biopsies from 60 transplanted and native kidneys have been processed and a prospective analysis of pattern, intensity and distribution of immunoglobulin deposits (IgA, IgG and IgM) and complement components (C3c and C1q) identified in these ...
Zinaida Karasalihović, Ermina Iljazović, Dušan Ferluga, Elmir Čičkušić, Jasminka Mustedanagić Mujanović, Jugoslav Stahov, Ina Škaljić   +6 more
doaj   +1 more source

Implementation Punctuation: The Role of Feedback, Narratives, and Implementation in the Punctuated Equilibrium Theory

Policy Studies Journal, Volume 54, Issue 2, May 2026.
ABSTRACT Based on the Punctuated Equilibrium Theory (PET) and implementation research, this study proposes an extended conceptualization of policy punctuation that enables researchers to systematically include policy implementation as part of a punctuation. The key mechanisms underlying the PET, i.e., policy image and venue, information processing, and
Bettina Stauffer
wiley   +1 more source

Distinct Pharmacodynamic Complement Biomarker Signatures Define Iptacopan and Pegcetacoplan Treatment in C3 Glomerulopathy

Kidney International Reports
Introduction: C3 glomerulopathy (C3G) is driven by alternative pathway (AP) dysregulation. Iptacopan inhibits factor B, whereas pegcetacoplan inhibits C3/C3b, suggesting distinct pharmacodynamic (PD) biomarker profiles.
Yuzhou Zhang, Héctor Martín Merinero, Anna R. Carmen, Kameron Kruger, Renee X. Goodfellow, Dingwu Shao, Sarah M. Roberts, Angela F.M. Nelson, Nicole C. Meyer Horning, Sydney S. Jellison, Didier Mandelbrot, Neetika Garg, Carla M. Nester, Richard J.H. Smith   +13 more
doaj   +1 more source