Results 51 to 60 of about 790,520 (218)

Blood protein adsorption onto chitosan [PDF]

open access: yes, 2002
Chitosan was recently indicated to enhance osteogenesis, improve wound healing but to activate the coagulation and the complement systems. In the present study approximately 10nm thick chitosan film were prepared on aminopropyltriethoxysilane (APTES ...
Benesch, Johan, Tengvall, P.
core   +1 more source

Proteomic Analysis of Complement Proteins in Glomerular Diseases.

open access: yesKidney International Reports, 2023
Introduction Complement plays an important role in the pathogenesis of glomerulonephritis (GN). Even though the underlying etiology of GN might be different, complement activation with subsequent glomerular deposition of complement proteins result in ...
S. Sethi   +3 more
semanticscholar   +1 more source

Is Early Complement Activation in Renal Transplantation Associated with Later Graft Outcome?

open access: yesKidney & Blood Pressure Research, 2018
Background/Aims: Complement activation is important in post-transplantation renal injury, but data on its role as predictor of transplant outcome/complications when assessed in donor kidneys are lacking.
Steffen Bobka   +7 more
doaj   +1 more source

Traffic-related air pollution and incident type 2 diabetes : results from the SALIA cohort study [PDF]

open access: yes, 2010
BACKGROUND: Cross-sectional and ecological studies indicate that air pollution may be a risk factor for type 2 diabetes, but prospective data are lacking.
Ursula Krämer   +8 more
core   +1 more source

Altered Expression of Complement Regulatory Proteins CD35, CD46, CD55, and CD59 on Leukocyte Subsets in Individuals Suffering From Coronary Artery Disease

open access: yesFrontiers in Immunology, 2019
Studies conducted in animal models have suggested that membrane complement regulatory proteins play an important role in the pathophysiology of coronary artery disease (CAD).
Nitesh Mishra   +7 more
doaj   +1 more source

Autoantibodies Against C3b—Functional Consequences and Disease Relevance

open access: yesFrontiers in Immunology, 2019
The complement component C3 is at the heart of the complement cascade. It is a complex protein, which generates different functional activated fragments (C3a, C3b, iC3b, C3c, C3d).
Vasil V. Vasilev   +13 more
doaj   +1 more source

Complement component C3: A structural perspective and potential therapeutic implications.

open access: yesSeminars in Immunology, 2022
As the most abundant component of the complement system, C3 and its proteolytic derivatives serve essential roles in the function of all three complement pathways.
B. Geisbrecht, John D Lambris, P. Gros
semanticscholar   +1 more source

HIV induces expression of complement component C3 in astrocytes by NF-κB-dependent activation of interleukin-6 synthesis [PDF]

open access: yes, 2017
Background Abnormal activation of the complement system contributes to some central nervous system diseases but the role of complement in HIV-associated neurocognitive disorder (HAND) is unclear.
Borjabad, Alejandra   +8 more
core   +2 more sources

Complement Activation via the Lectin and Alternative Pathway in Patients With Severe COVID-19

open access: yesFrontiers in Immunology, 2022
Complement plays an important role in the direct defense to pathogens, but can also activate immune cells and the release of pro-inflammatory cytokines. However, in critically ill patients with COVID-19 the immune system is inadequately activated leading
Janina Niederreiter   +7 more
semanticscholar   +1 more source

The relationship of anti-phospholipase A2 receptor antibody and C5a complement with disease activity and short-term outcome in idiopathic membranous nephropathy

open access: yesJournal of the Formosan Medical Association, 2019
Background: The binding of anti-phospholipase A2 receptor (anti-PLA2R) antibody to podocyte and complement activation is the mechanisms of idiopathic membranous nephropathy (IMN).
Jyun Ni Chi   +9 more
doaj   +1 more source

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