Results 51 to 60 of about 3,130 (159)

Xenotransplantation Literature Update: January–June 2026

Xenotransplantation, Volume 33, Issue 4, July/August 2026.
ABSTRACT In the first half of 2026, xenotransplantation advanced through refinement rather than dramatic new clinical milestones. Clinical studies described graft physiology, immune infiltration, complement activation, coagulation incompatibility, and early function in living recipients, decedent models, and clinical islet xenotransplantation ...
Kasra Shirini, Joseph M. Ladowski, Niket Harsh, Raphael P. H. Meier   +3 more
wiley   +1 more source

Development of a C3c-based ELISA method for the determination of anti-complementary potency of Bupleurum polysaccharides

Acta Pharmaceutica Sinica B, 2015
Traditionally, determination of inhibitory potency of complement inhibitors is performed by the hemolytic assay. However, this assay is not applicable to the lectin pathway, thus impeding the understanding of complement inhibitors against the overall ...
Mulu Wu, Hong Li, Yunyi Zhang, Daofeng Chen   +3 more
doaj   +1 more source

Complement Activation and Organ Damage After Trauma—Differential Immune Response Based on Surgical Treatment Strategy

Frontiers in Immunology, 2020
Background: The complement system is part of the innate immunity, is activated immediately after trauma and is associated with adult respiratory distress syndrome, acute lung injury, multiple organ failure, and with death of multiply injured patients ...
Ina Lackner, Birte Weber, Meike Baur, Giorgio Fois, Florian Gebhard, Roman Pfeifer, Paolo Cinelli, Sascha Halvachizadeh, Miriam Lipiski, Nikola Cesarovic, Hubert Schrezenmeier, Hubert Schrezenmeier, Markus Huber-Lang, Hans-Christoph Pape, Miriam Kalbitz   +14 more
doaj   +1 more source

Role of Prednisone and 25‐Hydroxyvitamin D on Bone Mineral Density and Osteoporosis in Systemic Lupus Erythematosus

Arthritis Care &Research, Volume 78, Issue 6, Page 743-748, June 2026.
Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi, Andrea Fava, Daniel W. Goldman, Laurence S. Magder, Michelle Petri   +4 more
wiley   +1 more source

Hypertension in Living Kidney Donors Has No Effect on Complement Activation and Fibrosis

Kidney & Blood Pressure Research
Introduction: In the past, elevated blood pressure was considered an exclusion criterion for living kidney donation because of concerns about premature kidney failure. Hypertension leads to complement deposits and renal fibrosis in the kidney.
Nadine Wagner, Miriam Angeloni, Fulvia Ferrazzi, Janina Müller-Deile, Maike Büttner-Herold, Kerstin Amann, Christoph Daniel, Eva Vonbrunn   +7 more
doaj   +1 more source

Complement activation in experimental and human temporal lobe epilepsy

Neurobiology of Disease, 2007
We investigated the involvement of the complement cascade during epileptogenesis in a rat model of temporal lobe epilepsy (TLE), and in the chronic epileptic phase in both experimental as well as human TLE.
E. Aronica, K. Boer, E.A. van Vliet, S. Redeker, J.C. Baayen, W.G.M. Spliet, P.C. van Rijen, D. Troost, F.H. Lopes da Silva, W.J. Wadman, J.A. Gorter   +10 more
doaj   +1 more source

Yi Shen An, a Chinese traditional prescription, ameliorates membranous glomerulonephritis induced by cationic bovine serum albumin in rats

Pharmaceutical Biology, 2022
Context Yi Shen An (YSA) is an investigational composite of traditional Chinese medicine (Reference: 2010L000974) for the treatment of renal disease.
Yun-Li Zhao, Xiang-Hua Zhang, Feng Guo, Ying Wei, Jian-Hua Shang, Xiao-Dong Luo   +5 more
doaj   +1 more source

Long‐Term Anifrolumab Treatment Normalizes Hematologic Parameters and Several Serologic Markers in Patients With Systemic Lupus Erythematosus

ACR Open Rheumatology, Volume 8, Issue 6, June 2026.
Objective To evaluate the long‐term effects of anifrolumab on hematologic and serologic parameters over four years. Methods This analysis included 536 patients with moderate‐to‐severe systemic lupus erythematosus (SLE) who received intravenous anifrolumab 300 mg (n = 358) or placebo (n = 178) in the 52‐week, phase 3 TULIP‐1/2 trials (NCT02446912 and ...
Edward M. Vital, Zahir Amoura, Kenneth C. Kalunian, Ian N. Bruce, Yoshiya Tanaka, Susan Manzi, Ihor Hupka, Jacob Knagenhjelm, Hussein Al‐Mossawi, Catharina Lindholm   +9 more
wiley   +1 more source

Immune complexes and complement in serum and synovial fluid of rheumatoid arthritis patients [PDF]

Journal of Medical Biochemistry, 2009
Rheumatoid arthritis (RA) is predominantly an intraarticular inflammatory and autoimmune disease that involves different autoantibodies and effector mechanisms.
Mijušković Zoran, Rackov Ljiljana, Pejović Janko, Živanović Sandra, Stojanović Jelica, Kovačević Zoran   +5 more
doaj  

Functional Hyperthermia Presenting as Fever of Unknown Origin With Normal Inflammatory Markers in an Adolescent

Journal of General and Family Medicine, Volume 27, Issue 5, September 2026.
Ryuichi Minoda Sada, Hirofumi Miyake, Hiroyuki Akebo, Kazuhiro Hatta   +3 more
wiley   +1 more source