Results 41 to 50 of about 3,342 (187)

Complement System in the Pathogenesis of Benign Lymphoepithelial Lesions of the Lacrimal Gland. [PDF]

PLoS ONE, 2016
We aimed to examine the potential involvement of local complement system gene expression in the pathogenesis of benign lymphoepithelial lesions (BLEL) of the lacrimal gland.We collected data from 9 consecutive pathologically confirmed patients with BLEL ...
Jing Li, Xin Ge, Xiaona Wang, Xiao Liu, Jianmin Ma   +4 more
doaj   +1 more source

Altered Expression of Complement Regulatory Proteins CD35, CD46, CD55, and CD59 on Leukocyte Subsets in Individuals Suffering From Coronary Artery Disease

Frontiers in Immunology, 2019
Studies conducted in animal models have suggested that membrane complement regulatory proteins play an important role in the pathophysiology of coronary artery disease (CAD).
Nitesh Mishra, Madhav Mohata, Rajeev Narang, R. Lakshmy, Anjali Hazarika, R. M. Pandey, Nibhriti Das, Kalpana Luthra   +7 more
doaj   +1 more source

Complement activation in severely ill patients with sepsis: no relationship with inflammation and disease severity

Critical Care, 2023
Background Sepsis is characterized by a dysregulated immune response to infection. The complement system plays an important role in the host defence to pathogens.
Aline H. de Nooijer, Antigone Kotsaki, Eleftheria Kranidioti, Matthijs Kox, Peter Pickkers, Erik J. M. Toonen, Evangelos J. Giamarellos-Bourboulis, Mihai G. Netea   +7 more
doaj   +1 more source

Autoantibodies Against C3b—Functional Consequences and Disease Relevance

Frontiers in Immunology, 2019
The complement component C3 is at the heart of the complement cascade. It is a complex protein, which generates different functional activated fragments (C3a, C3b, iC3b, C3c, C3d).
Vasil V. Vasilev, Maria Radanova, Valentin J. Lazarov, Marie-Agnes Dragon-Durey, Marie-Agnes Dragon-Durey, Marie-Agnes Dragon-Durey, Marie-Agnes Dragon-Durey, Veronique Fremeaux-Bacchi, Veronique Fremeaux-Bacchi, Veronique Fremeaux-Bacchi, Veronique Fremeaux-Bacchi, Lubka T. Roumenina, Lubka T. Roumenina, Lubka T. Roumenina   +13 more
doaj   +1 more source

Correlation of C3c complement, NT-pro BNP and Left Ventricle Ejection Fraction in Heart Failure [PDF]

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2019
Introduction. Heart failure is a health problem in Indonesia. The 2013 Basic Health Research Data showed that the estimated heart failure in Indonesia was 530,068 people. Echocardiography examination which has been a routine examination of heart failure patients is not necessarily available in all hospitals, so that a more applicable and inexpensive ...
Julious Julious, Jusak Nugraha, Mohammad Aminuddin   +2 more
openaire   +1 more source

Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin–Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H–Related Protein-5 (FHR5) Deposition

Kidney International Reports, 2018
IgA nephropathy (IgAN) is characterized by glomerular deposition of galactose-deficient IgA1 and complement proteins and leads to renal impairment. Complement deposition through the alternative and lectin activation pathways is associated with renal ...
Nicholas R. Medjeral-Thomas, Anne Troldborg, Nicholas Constantinou, Hannah J. Lomax-Browne, Annette G. Hansen, Michelle Willicombe, Charles D. Pusey, H. Terence Cook, Steffen Thiel, Matthew C. Pickering   +9 more
doaj   +1 more source

The relationship of anti-phospholipase A2 receptor antibody and C5a complement with disease activity and short-term outcome in idiopathic membranous nephropathy

Journal of the Formosan Medical Association, 2019
Background: The binding of anti-phospholipase A2 receptor (anti-PLA2R) antibody to podocyte and complement activation is the mechanisms of idiopathic membranous nephropathy (IMN).
Jyun Ni Chi, Tai Shuan Lai, Ching Fang Wu, Tian Yi Fu, Yu Hsiang Chou, Yen Ling Chiu, Wei Chou Lin, Wen Chih Chiang, Yung Ming Chen, Ming Shiou Wu   +9 more
doaj   +1 more source

Teacher Well‐Being Across Career Stages: An Ecological Study of Early‐ and Mid‐Career English Teachers in Japanese Secondary Schools

International Journal of Applied Linguistics, EarlyView.
ABSTRACT Teacher well‐being has garnered increasing attention in language education, as it plays a vital role in shaping both their professional lives and student learning. Although its importance is recognised, further research is still needed to gain a more comprehensive understanding of language teachers' well‐being.
Takeshi Onodera
wiley   +1 more source

Sequential Increase in Complement Factor I, iC3b, and Cells Expressing CD11b or CD14 in Cutaneous Vasculitis

Analytical Cellular Pathology, 2022
Mast cells contribute to the pathogenesis of cutaneous vasculitis through complement C3 that is cleaved to C3b and then to iC3b by complement factor I. The receptor of iC3b, CD11b, is expressed on neutrophils and monocytes and CD14 on monocytes.
Dina Rahkola, Tiina Lipitsä, Hanna Siiskonen, Anita Naukkarinen, Ilkka T. Harvima   +4 more
doaj   +1 more source

Role of Prednisone and 25‐Hydroxyvitamin D on Bone Mineral Density and Osteoporosis in Systemic Lupus Erythematosus

Arthritis Care &Research, Volume 78, Issue 6, Page 743-748, June 2026.
Objective We evaluated the role of 25‐hydroxyvitamin D (25[OH]D), prednisone, and other risk factors for bone mineral density (BMD) loss and osteoporosis in systemic lupus erythematosus (SLE). Methods We calculated the association between 25(OH)D levels and other potential risk factors and BMD measures (spine T scores) and osteoporosis (defined as a T ...
Nima Madanchi, Andrea Fava, Daniel W. Goldman, Laurence S. Magder, Michelle Petri   +4 more
wiley   +1 more source