Results 21 to 30 of about 3,130 (159)

Utility of anti-immunoglobulin IgA, IgG, IgM, Kappa, Lambda - FITC (conjugate) cocktail in routine renal pathology practice

Surgical and Experimental Pathology, 2023
Background Immunofluorescence studies on frozen sections are an essential component in the evaluation of renal biopsies. The basic panel in most centres constitutes IgG, IgA, IgM, C3c, C1q, Kappa and Lambda light chain antibody testing.
Shilpi Thakur, Balan Louis Gaspar
doaj   +1 more source

Overactivation of the complement system may be involved in intrarenal arteriolar lesions in IgA nephropathy

Frontiers in Medicine, 2022
IntroductionIgA nephropathy (IgAN) encompasses a wide range of clinical and histology features. Some patients present without hematuria, with or without hypertension, still rapidly progress in renal function. Renal pathology of this part of patients were
Wei-yi Guo, Xiu-ping An, Li-jun Sun, Hong-rui Dong, Wen-rong Cheng, Nan Ye, Guo-qin Wang, Xiao-yi Xu, Zhi-rui Zhao, Hong Cheng   +9 more
doaj   +1 more source

Complement Activation in Kidneys of Patients With COVID-19

Frontiers in Immunology, 2021
Most patients who became critically ill following infection with COVID-19 develop severe acute respiratory syndrome (SARS) attributed to a maladaptive or inadequate immune response.
Frederick Pfister, Eva Vonbrunn, Tajana Ries, Hans-Martin Jäck, Klaus Überla, Günter Lochnit, Ahmed Sheriff, Martin Herrmann, Maike Büttner-Herold, Kerstin Amann, Christoph Daniel   +10 more
doaj   +1 more source

Putative salivary protein biomarkers for the diagnosis of oral lichen planus: a case-control study

BMC Oral Health, 2018
Background Salivary protein biomarkers for screening and diagnosis of oral lichen planus (OLP) are not well-defined. The objective of this study was to identify putative protein biomarkers for OLP using proteomic approaches.
Sineepat Talungchit, Waranun Buajeeb, Chotima Lerdtripop, Rudee Surarit, Kongthawat Chairatvit, Sittiruk Roytrakul, Hiroaki Kobayashi, Yuichi Izumi, Siribang-on Piboonniyom Khovidhunkit   +8 more
doaj   +1 more source

New Insights into Xenotransplantation for Cartilage Repair: Porcine Multi-Genetically Modified Chondrocytes as a Promising Cell Source

Cells, 2021
Transplantation of xenogenic porcine chondrocytes could represent a future strategy for the treatment of human articular cartilage defects. Major obstacles are humoral and cellular rejection processes triggered by xenogenic epitopes like α-1,3-Gal and ...
Hanna Tritschler, Konrad Fischer, Jochen Seissler, Jörg Fiedler, Rebecca Halbgebauer, Markus Huber-Lang, Angelika Schnieke, Rolf E. Brenner   +7 more
doaj   +1 more source

Complement in acute and chronic arthritides: assessment of C3c, C9, and protectin (CD59) in synovial membrane. [PDF]

Annals of the Rheumatic Diseases, 1996
To investigate the role of complement cascade induced damage and protection against it in acute arthritides compared to rheumatoid arthritis and other chronic joint derangements.C3c, C9, and protectin (CD59) were examined by avidin-biotin-peroxidase complex staining.Marked deposits of C3c and C9 were found in synovial vasculature and intercellular ...
Y T, Konttinen, A, Ceponis, S, Meri, A, Vuorikoski, P, Kortekangas, T, Sorsa, A, Sukura, S, Santavirta   +7 more
openaire   +2 more sources

C3c intrathecal synthesis evaluation in patients with multiple sclerosis Evaluación de la síntesis intratecal de C3c en pacientes con esclerosis múltiple

Arquivos de Neuro-Psiquiatria, 2007
INTRODUCTION: Multiple sclerosis (MS) is a chronic, inflammatory and progressive disease of the central nervous system in which local inflammatory injuries of the brain white matter appears, being the most outstanding feature the myeline loss ...
Bárbara Padilla-Docal, Alberto J Dorta-Contreras, Hermes Fundora-Hernández, Elena Noris-García, Raisa Bu-Coifiu-Fanego, Marlen González-Hernández, Alexis Rodríguez-Rey   +6 more
doaj   +1 more source

Is Early Complement Activation in Renal Transplantation Associated with Later Graft Outcome?

Kidney & Blood Pressure Research, 2018
Background/Aims: Complement activation is important in post-transplantation renal injury, but data on its role as predictor of transplant outcome/complications when assessed in donor kidneys are lacking.
Steffen Bobka, Nadja Ebert, Eloed Koertvely, Johannes Jacobi, Michael Wiesener, Maike Büttner-Herold, Kerstin Amann, Christoph Daniel   +7 more
doaj   +1 more source

New Technology Capabilities of Direct Antiglobulin Test

Клиническая онкогематология, 2020
Background. Direct antiglobulin test (DAT) is used to identify erythrocyte-fixed antibodies and complement components. Gel methods are applied to differentiate immunoglobulin class and subclass in positive DAT, which allows to study the nature of anemia ...
Elena Aleksandrovna Poponina, E. V. Butina, A. V. Iovdii, O. D. Maksimov, G. A. Zaitseva, I. V. Paramonov   +5 more
doaj   +1 more source

The loss of glycocalyx integrity impairs complement factor H binding and contributes to cyclosporine-induced endothelial cell injury

Frontiers in Medicine, 2023
BackgroundCalcineurin inhibitors (CNIs) are associated with nephrotoxicity, endothelial cell dysfunction, and thrombotic microangiopathy (TMA). Evolving evidence suggests an important role for complement dysregulation in the pathogenesis of CNI-induced ...
Chia Wei Teoh, Chia Wei Teoh, Chia Wei Teoh, Chia Wei Teoh, Magdalena Riedl Khursigara, Magdalena Riedl Khursigara, Magdalena Riedl Khursigara, Carolina G. Ortiz-Sandoval, Jee Woo Park, Jun Li, Arlette Bohorquez-Hernandez, Valentina Bruno, Valentina Bruno, Valentina Bruno, Emily E. Bowen, Spencer A. Freeman, Spencer A. Freeman, Lisa A. Robinson, Lisa A. Robinson, Lisa A. Robinson, Lisa A. Robinson, Christoph Licht, Christoph Licht, Christoph Licht, Christoph Licht, Christoph Licht   +25 more
doaj   +1 more source