Results 11 to 20 of about 3,130 (159)

Intrathecal synthesis of complement components C3c and C4 in the central nervous system infections with signs of the acute serous meningitis syndrome [PDF]

Vojnosanitetski Pregled, 2002
Two hundred and ten patients with meningismus and the infections of the central nervous system (CNS) with the clinical symptoms and signs of the acute serous meningitis syndrome, were divided into groups according to etiology (enterovirus meningitis ...
Tatomirović Željka, Bokun Radojka, Bokonjić Dubravko   +2 more
doaj   +3 more sources

Redefined complement C3c structures have significant increase in the plasma of ovarian cancer patients. [PDF]

J Chin Med Assoc
Background: Ovarian cancer (OC) is the third most common gynecological cancer. Effective biomarkers are required for OC as in the case of other cancers. Therefore, here we explored whether plasma proteolytic products could serve as potential biomarkers.
Chen DH, Chang YW, Chien CH, Torng PL, Tsay YG.   +4 more
europepmc   +4 more sources

Increased expression of complement C3c, iC3b, and cells containing CD11b or CD14 in experimentally induced psoriatic lesion. [PDF]

Clin Exp Immunol
Abstract Psoriasis is a chronic inflammatory skin disease with a characteristic isomorphic reaction, i.e. the Köbner reaction, induced by slight epidermal trauma. In this study, the tape-stripping technique was used to induce the development of Köbner reaction in 18 subjects with psoriasis.
Rahkola D, Harvima RJ, Harvima IT.
europepmc   +3 more sources

Complement, but Not Platelets, Plays a Pivotal Role in the Outcome of Mucormycosis In Vivo

Journal of Fungi, 2023
Background: Mucormycetes, a heterogeneous group of fungi, induce a life-threatening disease called mucormycosis. Immune deficiencies represent a major risk factor; hence, we wanted to illuminate the role of complement and platelets in the defense against
Verena Harpf, Günter Rambach, Nadia Parth, Magdalena Neurauter, Verena Fleischer, Michaela Lackner, Cornelia Lass-Flörl, Reinhard Würzner, Cornelia Speth   +8 more
doaj   +1 more source

Complement alternative pathway activation in human nonalcoholic steatohepatitis. [PDF]

PLoS ONE, 2014
The innate immune system plays a major role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Recently we reported complement activation in human NASH.
Filip M Segers, Froukje J Verdam, Charlotte de Jonge, Bas Boonen, Ann Driessen, Ronit Shiri-Sverdlov, Nicole D Bouvy, Jan Willem M Greve, Wim A Buurman, Sander S Rensen   +9 more
doaj   +1 more source

Complement split product C3c in saliva as biomarker for periodontitis and response to periodontal treatment [PDF]

Journal of Periodontal Research, 2020
AbstractBackground and ObjectiveThe complement system is engaged in inflammatory reactions both in the periodontal pockets and in the periodontium itself, where it can mediate tissue destruction. The aim of this study was, first, to compare salivary levels of the total complement system protein C3 and its split product, fluid‐phase C3c in patients with
Maria Anastasia Grande, Daniel Belstrøm, Christian Damgaard, Palle Holmstrup, Sai Sindhu Thangaraj, Claus Henrik Nielsen, Yaseelan Palarasah   +6 more
openaire   +5 more sources

Haemolytic complement activity and C3c serum concentration in pigs [PDF]

Archives Animal Breeding, 1999
Abstract. Because of the importance of the complement system in disease resistance through direct lysis of target cells and support of other mechanisms of the immune System, individual Variation in haemolytic complement activity and C3 concentration in pigs prior and after vaccination were evaluated.
Wimmer, K., Lipperheide, C., Ponsuksili, S., Schmoll, F., Hardge, T., Petersen, B., Schellander, K.   +6 more
openaire   +2 more sources

Dysregulated biomarkers of innate and adaptive immunity predict infections and disease progression in cirrhosis

JHEP Reports, 2023
Background & Aims: Cirrhosis-associated immune dysfunction (CAID) affects both innate and adaptive immunity. This study investigated the complement system, immunoglobulins, and acute-phase proteins and their prognostic relevance in patients with ...
Benedikt Simbrunner, Lukas Hartl, Mathias Jachs, David J.M. Bauer, Bernhard Scheiner, Benedikt Silvester Hofer, Albert Friedrich Stättermayer, Rodrig Marculescu, Michael Trauner, Mattias Mandorfer, Thomas Reiberger   +10 more
doaj   +1 more source

Complement C3c Reflects Acute-Phase Response but Not Clinical Phenotype in Systemic Sclerosis: A Cross-Sectional Study. [PDF]

Int J Mol Sci
This study evaluated routinely measured serum complement C3c (C3c) and complement C4 (C4) in relation to systemic inflammation, clinical and immunological phenotypes, and patient-reported outcomes (PROs) in systemic sclerosis (SSc). Seventy SSc patients fulfilling the 2013 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR ...
Trefler J, Pasierb A, Lech L, Czaplicki H, Życińska K.   +4 more
europepmc   +2 more sources

C3c沉积可预测2型糖尿病患者经活检证实的糖尿病肾病更差的肾脏结局

Journal of Diabetes, 2022
Background Although extensive efforts have been paid to identify reliable predictors for renal outcomes of diabetic kidney disease (DKD) patients in type 2 diabetes mellitus (T2DM), there are still only a limited number of predictive factors for DKD ...
Meng‐Rui Li, Zi‐Jun Sun, Dong‐Yuan Chang, Xiao‐Juan Yu, Su‐Xia Wang, Min Chen, Ming‐Hui Zhao   +6 more
doaj   +1 more source