Results 71 to 80 of about 3,130 (159)

A study of detection and comparison of immunofluorescence on formalin-fixed paraffin-embedded tissue with fresh frozen renal biopsy specimen

Saudi Journal of Kidney Diseases and Transplantation, 2019
Direct immunofluorescence on the fresh frozen tissue is established way of demonstrating of immunoglobulins and complement deposition in renal biopsies. IF studies can be done on paraffin-fixed tissue (IF-P) and give comparable results to those obtained ...
Ranjana Solanki, Madan Kumar Solanki, Deepika Hemrajani, Jayesh Saha   +3 more
doaj   +1 more source

Claudin-2 enhances human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells by modulating antibody binding and complement activation

Frontiers in Immunology
BackgroundImmune rejection represents a significant barrier to transplantation, especially in the context of xenotransplantation. Endothelial cells (ECs) derived from pigs serve as the initial barrier against the human immune system in ...
Weilong Li, Fang Yang, Dexin Yang, Zhuoheng Song, Zigan Xu, Jinmei Wu, Yanmei Li, Zixi Chen, Peishan Chen, Yeye Yu, Ting Xie, Cuishan Yang, Liying Zhou, Shaodong Luan, Hanchao Gao   +14 more
doaj   +1 more source

Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy

Frontiers in Immunology, 2018
Membranous nephropathy is an immune kidney disease caused by IgG antibodies that form glomerular subepithelial immune complexes. Proteinuria is mediated by complement activation, as a result of podocyte injury by C5b-9, but the role of specific ...
Wentian Luo, Wentian Luo, Florina Olaru, Florina Olaru, Jeffrey H. Miner, Laurence H. Beck, Johan van der Vlag, Joshua M. Thurman, Dorin-Bogdan Borza, Dorin-Bogdan Borza   +9 more
doaj   +1 more source

A comparative proteomic study of sera in paediatric systemic lupus erythematosus patients and in healthy controls using MALDI-TOF-TOF and LC MS–A pilot study

Pediatric Rheumatology Online Journal, 2012
Background Paediatric systemic lupus erythematosus (pSLE) exhibits an aggressive clinical phenotype with severe complications and overall poor prognosis.
Rana Anita, Minz Ranjana W, Aggarwal Ritu, Sharma Sadhna, Pasricha Neelam, Anand Shashi, Singh Surjit   +6 more
doaj   +1 more source

Complement levels and their diagnostic utility in neonatal sepsis

BMC Pediatrics
Background This study evaluated the diagnostic value of complement levels in neonatal sepsis and their roles in disease progression. Methods This diagnostic accuracy study, conducted in Guangdong Province, China (January 2021-February 2022), involved 41 ...
Fuqiang Diao, Feng Zhong, Lingling Tang, Chunming Gu, Junfei Guo, Lihong Wu, Weixiang Wu, Mingyong Luo   +7 more
doaj   +1 more source

Complement activation products in the circulation and urine of primary membranous nephropathy

BMC Nephrology, 2019
Background Complement activation plays a substantial role in the pathogenesis of primary membranous nephropathy (pMN). C5b-9, C3c, MBL, and factor B have been documented in the subepithelial immune deposits. However, the changing of complement activation
Mu-fan Zhang, Jing Huang, Yi-miao Zhang, Zhen Qu, Xin Wang, Fang Wang, Li-qiang Meng, Xu-yang Cheng, Zhao Cui, Gang Liu, Ming-hui Zhao   +10 more
doaj   +1 more source

A case of glomerulonephritis with dominant C3 with organized deposits complicated by non-tuberculous mycobacteria

Human Pathology Reports
We report a case of membranoproliferative glomerulonephritis (MPGN) with dominant C3 and uniquely organized deposits complicated by pulmonary non-tuberculous mycobacterial (NTM) infection.
Masanori Sudo, Chihiro Sakurazawa, Yuichi Sakamaki, Masato Habuka, Asa Ogawa, Yumi Ito, Naofumi Imai, Sayuri Takamura, Satoshi Ito, Akira Shimizu, Shin Goto, Suguru Yamamoto   +11 more
doaj   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

[Determination of the fraction of C3c complement by radial immunodiffusion in the serum and saliva from the parotid gland of clinically normal subjects].

Revista do Hospital das Clinicas, 1991
It was our intention to determine the C3c fraction in the serum and in the parotid saliva of 13 clinically normal individuals by the radial immunodiffusion method. The mean value of the seric C3c was 86.92 mg/dl and the confidence levels averaged 75.53 to 100.31 mg/dl. There was no measurable concentration of C3c in the parotid saliva.
A C, de Campos, V P, Galletta, W, Cossermelli, M V, Gayotto   +3 more
openaire   +1 more source

Association of FHR5 With Disease Severity in ANCA-Associated Vasculitis. [PDF]

Kidney Int Rep
Li YJ, Chen SF, Li ZY, Zhu L, Wang SX, Zhao MH, Little MA, Chen M.   +7 more
europepmc   +1 more source