Results 71 to 80 of about 790,520 (218)

Role of complement activation in cellular activation by systemic lupus erythematosus (SLE) immune complexes (ICs)

Journal of Immunology, 2023
Complement (C’) activation is a prominent feature of SLE ICs, but the mechanism by which C’ mediates cellular activation by ICs is not well understood.
S. Khandelwal, Sooho Myoung, John D Lambris, Jennifer L. Rogers, D. Pisetsky, G. Arepally   +5 more
semanticscholar   +1 more source

Implementation Punctuation: The Role of Feedback, Narratives, and Implementation in the Punctuated Equilibrium Theory

Policy Studies Journal, EarlyView.
ABSTRACT Based on the Punctuated Equilibrium Theory (PET) and implementation research, this study proposes an extended conceptualization of policy punctuation that enables researchers to systematically include policy implementation as part of a punctuation. The key mechanisms underlying the PET, i.e., policy image and venue, information processing, and
Bettina Stauffer
wiley   +1 more source

Tolerability and Feasibility of Minimally Invasive Canine Skin Sampling: Excellent Tolerability Meets Transcriptomic Challenges

Veterinary Dermatology, EarlyView.
ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann, Lisa B. Mamo, Allison N. Dickey   +2 more
wiley   +1 more source

Regulators of complement activity mediate inhibitory mechanisms through a common C3b‐binding mode [PDF]

, 2016
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Atkinson, John P, Bertram, Paula, Forneris, Federico, Granneman, Joke CM, Gros, Piet, Hauhart, Richard, Lambris, John D, Lin, Zhuoer, Liszewski, M. Kathryn, Ricklin, Daniel, Sfyroera, Georgia, Tzekou, Apostolia, Volokhina, Elena, Wu, Jin, Xue, Xiaoguang   +14 more
core   +2 more sources

Unraveling the Mystery of Melt Migration in Migmatites: From Channeling Instability to Pattern Formation

Journal of Geophysical Research: Solid Earth, Volume 131, Issue 5, May 2026.
Abstract Melt migration in partially molten rocks is commonly described by porous flow models controlled by the hydro‐mechanical compaction length, which effectively explains melt extraction at mid‐ocean ridges. However, this framework cannot account for the paradoxical accumulation of small melt fractions into rhythmic leucosome–melanosome bands in ...
Qingpei Sun, Manman Hu, Roberto Weinberg, Klaus Regenauer‐Lieb   +3 more
wiley   +1 more source

Bee Venom Alleviates Atopic Dermatitis Symptoms through the Upregulation of Decay-Accelerating Factor (DAF/CD55)

Toxins, 2019
Bee venom (BV)—a complex mixture of peptides and toxic proteins including phospholipase A2 and melittin—promotes blood clotting. In this study, we investigated the anti-atopic properties of BV and the mechanism associated with its regulation ...
Yenny Kim, Youn-Woo Lee, Hangeun Kim, Dae Kyun Chung   +3 more
doaj   +1 more source

Alternative Complement Pathway Is Activated and Associated with Galactose-Deficient IgA1 Antibody in IgA Nephropathy Patients

Frontiers in Immunology, 2021
BackgroundGalactose-deficient IgA1 (Gd-IgA1) and alternative complement pathway activation are considered to be involved in the pathogenesis of IgA nephropathy (IgAN).
Yen-Ling Chiu, Yen-Ling Chiu, Yen-Ling Chiu, Wei-Chou Lin, Kai-Hsiang Shu, Yi-Wen Fang, Fan-Chi Chang, Yu-Hsiang Chou, Ching-Fang Wu, Wen-Chih Chiang, Shuei-Liong Lin, Shuei-Liong Lin, Yung-Ming Chen, Ming-Shiou Wu   +13 more
doaj   +1 more source

Die Insuffizienz der intraabdominellen Infektabwehr bei der eitrigen Peritonitis [PDF]

, 1989
Despite a high concentration of serum proteins and intact phagocytes peritonitis exudates contain a large number of viable, pathogenic bacteria. The reason for this biological paradox is unknown.
Billing, A., Fröhlich, D., Jochum, Marianne, Kortmann, H.   +3 more
core   +1 more source

Complement activation in septic baboons detected by neoepitope-specific assays for C3b/iC3b/C3c, C5a and the terminal C5b-9 complement complex (TCC)

Clinical and Experimental Immunology, 1993
SUMMARYWe have investigated the cross-reactivity of various species in ncocpitope-specific methods for quantification of human complement aclivatlon products. In contrast to most other species examined, baboon showed a substantial cross-reactivity supporting a high degree of homology between human and bahoon complement.
T E, Mollnes, H, Redl, K, Høgåsen, A, Bengtsson, P, Garred, L, Speilberg, T, Lea, M, Oppermann, O, Götze, G, Schlag   +9 more
openaire   +3 more sources

Investigation of Potential Risks in Bio‐Based Food Contact Materials (FCMs) From Microbial Exploitation of Agricultural Wastes: Case Studies of Bacterial Cellulose and Nisin

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT In the context of the circular economy and the increasing demand for safe and sustainable packaging, this work addresses the safety assessment of food contact materials (FCMs) derived from agro‐industrial by‐products. Despite growing interest in these bio‐based materials, the literature still lacks a structured safety‐assessment framework able
Marianna Ciccone, Emmanouil Tsochatzis, Joel Armando Njieukam, Lorenzo Siroli, Davide Gottardi, Rosalba Lanciotti, Francesca Patrignani   +6 more
wiley   +1 more source