Results 211 to 220 of about 32,418 (239)

Recent advances in Mpox across innate immunity, evasion, and clinical outcomes. [PDF]

Commun Biol
Oh J, Chung YS, Lee S.
europepmc   +1 more source

Developing a critical caste analysis within information science and technology: A research review: An annual review of information science and technology paper

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Caste—an ascriptive social hierarchy in South Asia and its diaspora—is a globalized phenomenon. Recent caste‐based discrimination, particularly in technology companies and anti‐caste efforts to address it, has compelled academia, policy, and the technology industry to better understand contemporary mechanics of caste.
Nayana Kirasur, Britt Paris
wiley   +1 more source

Reprogramming innate immunity through viral interference: A double-edged strategy for enhancing and containing gene therapies. [PDF]

Mol Ther Nucleic Acids
Liu Z, Song S.
europepmc   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

Cellular and molecular interactions underlying the peripheral immune responses to blood-stage malaria infections. [PDF]

Immunohorizons
Tebben K, Asawa R, Serre D, Lyke KE.
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Chlamydia trachomatis orchestrates multifaceted host cell manipulation for immune evasion. [PDF]

Commun Biol
Krishnan Nair Geetha D, Agarwal P, Thiruvacholayil A, Rajeeve K.   +3 more
europepmc   +1 more source

<i>Avibacterium paragallinarum</i>: Pathogenesis Mechanisms and Subunit Vaccine Development. [PDF]

Microorganisms
Li Z, Liu Y, Liu Z, Jiang Z, Wang Y, Xing B, Mei C, Wang H.   +7 more
europepmc   +1 more source

Pathogen Evasion of Humoral Innate Immunity: Coping with C-Reactive Protein and Serum Amyloid A. [PDF]

Int J Mol Sci
Gong W, Cheng X, Villena J, Kitazawa H.
europepmc   +1 more source