Results 221 to 230 of about 505,979 (246)

Evolution of Physical Intelligence Across Scales

Advanced Intelligent Discovery, EarlyView.
By following the evolution of physical intelligence across scales, this article shows how intelligence arises from materials, structures, physical interactions, and collectives. It establishes physical intelligence as the evolutionary foundation upon which embodied intelligence is built.
Ke Liu, Tianyun Huang, Aming Li, Pengyu Lv, Tingting Qin, Wenhui Chen, Hui Wei, Huiling Duan   +7 more
wiley   +1 more source

A Multistrategy AI‐Assisted Consensus Screening Pipeline for Discovery of Candidate p53 Monomer Binders

Advanced Intelligent Discovery, EarlyView.
An ultra‐fast small‐sample AI consensus pipeline combines co‐folding and docking to target structure‐lacking p53 monomers. Its optimal mini‐protein binder shows robust interfacial affinity and promising druggability, supplying unprecedented antitumor p53 templates.
Ningyao Li, Xueyi Liu, Qiuyue Li, Chengfeng Yue, Xin Li, Yugang Huang, Xin Deng, Junfei Zhang, Xue Liang, Guodong Ye   +9 more
wiley   +1 more source

Herpes Simplex Virus: Molecular Pathogenesis, Type-Specific Disease Burden, and Advances in Prevention and Treatment. [PDF]

Viruses
Jiang C, Nie J, Zhang L.
europepmc   +1 more source

Artificial Intelligence for Benign Esophageal Stricture Dilation: An Evidence‐Transferability Framework and Safety‐First Roadmap

AI &Innovation, EarlyView.
ABSTRACT Background Endoscopic dilation is first‐line therapy for symptomatic benign esophageal strictures but remains operator‐dependent. Artificial intelligence (AI) could support assessment, risk stratification, and documentation; however, evidence from adjacent tasks is often mistaken for procedure‐specific validation.
Ahmed A. Salman, Mohamed A. Salman
wiley   +1 more source

Bacterial sialidases subvert the complement system through desialylation. [PDF]

Protein Sci
Kurniyati K, Clark ND, Fu Q, Zhang S, Qiu W, Malkowski MG, Li C.   +6 more
europepmc   +1 more source

<i>Candida</i><i>tropicalis</i>: An Emerging Opportunistic Pathogen at the Interface of Virulence, Antifungal Resistance, and Host Immune Interactions. [PDF]

Microorganisms
Gómez-Gaviria M, Baruch-Martínez DA, Mora-Montes HM.   +2 more
europepmc   +1 more source

Immuno-phage synergy driven by fitness costs: turning bacterial phage resistance into therapeutic gain through evolutionary traps. [PDF]

Front Immunol
Fujiki J, Yamada A, Shinzato R, Hiya R, Norihisa N, Imai K, Wakabayashi E, Gondaira S, Higuchi H, Iwano H.   +9 more
europepmc   +1 more source

Hypoimmune platforms: from rejection to immune evasion and regulatory implications. [PDF]

Transpl Int
Campo F, Bellini MI, Scholz H, Piemonti L, Citro A.   +4 more
europepmc   +1 more source

Tumor-Derived Complement C3 Overexpression in STK11-Mutant Lung Adenocarcinoma Drives Tumor Growth and Immune Checkpoint Inhibitor Resistance. [PDF]

Cancer Immunol Res
Suzuki S, Kandar B, Ting C, Deraska P, Chen TA, Giridharan T, Khan ANH, Attwood K, Yu H, Catalfamo K, Singh PK, Bushey RT, Gottlin EB, Campa MJ, Patz EF, Ajona D, Pio R, Segal BH, Yau EH.   +18 more
europepmc   +1 more source

Guiding pluripotent stem cell therapies past the immune system. [PDF]

Stem Cells Transl Med
Pizzato HA, Bhattacharya D.
europepmc   +1 more source