Results 61 to 70 of about 2,642,556 (405)

Complement factor H related proteins (CFHRs)

Molecular Immunology, 2013
Factor H related proteins comprise a group of five plasma proteins: CFHR1, CFHR2, CFHR3, CFHR4 and CFHR5, and each member of this group binds to the central complement component C3b. Mutations, genetic deletions, duplications or rearrangements in the individual CFHR genes are associated with a number of diseases including atypical hemolytic uremic ...
Véronique Frémeaux-Bacchi, Christine Skerka, Qian Chen, Lubka T. Roumenina, Lubka T. Roumenina, Lubka T. Roumenina   +5 more
openaire   +3 more sources

Translational Mini-Review Series on Complement Factor H: Genetics and disease associations of human complement factor H [PDF]

Clinical and Experimental Immunology, 2007
SummaryOTHER ARTICLES PUBLISHED IN THIS TRANSLATIONAL MINI-REVIEW SERIES ON COMPLEMENT FACTOR HStructural and functional correlations for factor H. Clin Exp Immunol 2008; 151: doi:10.1111/j.1365-2249.2007.03553.xTherapies of renal diseases associated with complement factor H abnormalities: atypical haemolytic uraemic syndrome and membranoproliferative ...
Rodríguez de Córdoba, Santiago, Goicoechea de Jorge, Elena   +1 more
openaire   +4 more sources

Upregulation of Complement Factor H by SOCS-1/3–STAT4 in Lung Cancer

Cancers, 2019
Complement factor H (CFH) is a fluid phase regulator of complement proteins and functions to prevent complement attack and immune surveillance. CFH is known to inactivate therapeutic antibody-dependent complement-mediated cellular cytotoxicity.
Yeon-Hee Yoon, Hyeon-Ji Hwang, Hye-Jin Sung, Sun‐Hee Heo, Dong-Sun Kim, Su-Hyung Hong, Kang-Hoon Lee, Je-Yoel Cho   +7 more
semanticscholar   +1 more source

Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis

Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen, Meng‐Meng Ji, Peng‐Peng Xu, Wei‐Li Zhao   +3 more
wiley   +1 more source

Parallel block preconditioners for virtual element discretizations of the time-dependent Maxwell equations [PDF]

, 2022
The focus of this study is the construction and numerical validation of parallel block preconditioners for low order virtual element discretizations of the three-dimensional Maxwell equations. The virtual element method (VEM) is a recent technology for the numerical approximation of partial differential equations (PDEs), that generalizes finite ...
arxiv   +1 more source

An Engineered Complement Factor H Construct for Treatment of C3 Glomerulopathy.

Journal of the American Society of Nephrology, 2018
Background C3 glomerulopathy (C3G) is associated with dysregulation of the alternative pathway of complement activation, and treatment options for C3G remain limited.
Yi Yang, Harriet Denton, O. Davies, K. Smith-Jackson, H. Kerr, A. Herbert, P. Barlow, M. Pickering, K. Marchbank   +8 more
semanticscholar   +1 more source

Effect of different noise reduction techniques and template matching parameters on markerless tumor tracking using dual‐energy imaging

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To evaluate the impact of various noise reduction algorithms and template matching parameters on the accuracy of markerless tumor tracking (MTT) using dual‐energy (DE) imaging. Methods A Varian TrueBeam linear accelerator was used to acquire a series of alternating 60 and 120 kVp images (over a 180° arc) using fast kV switching, on ...
Mandeep Kaur, Peter Wagstaff, Hassan Mostafavi, Mathias Lehmann, Daniel Morf, Liangjia Zhu, Hyejoo Kang, Michal Walczak, Matthew M. Harkenrider, John C. Roeske   +9 more
wiley   +1 more source

Complement Factor H and Apolipoprotein E Participate in Regulation of Inflammation in THP-1 Macrophages

Frontiers in Immunology, 2018
The alternative pathway (AP) of complement is constantly active in plasma and can easily be activated on self surfaces and trigger local inflammation. Host cells are protected from AP attack by Factor H (FH), the main AP regulator in plasma.
Eija Nissilä, Pipsa Hakala, Katarzyna Leskinen, Angela Roig, Shahan Syed, Kok P. M. Van Kessel, Jari Metso, Carla J. C. De Haas, Päivi Saavalainen, Seppo Meri, Angeliki Chroni, Jos A. G. Van Strijp, Katariina Öörni, Matti Jauhiainen, T. Sakari Jokiranta, Karita Haapasalo   +15 more
doaj   +1 more source

Functional evaluation of complement factor I variants by immunoassays and SDS-PAGE

Frontiers in Immunology, 2023
Factor I (FI) is an essential regulator of the complement system. Together with co-factors, FI degrades C3b, which inhibits further complement activation.
Alexandra Gerogianni, Alexandra Gerogianni, Laura M. Baas, Dick J. Sjöström, Dick J. Sjöström, Nicole C. A. J. van de Kar, Marit Pullen, Siem J. van de Peppel, Per H. Nilsson, Per H. Nilsson, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel   +13 more
doaj   +1 more source

Highly tree-connected complementary modulo factors with bounded degrees [PDF]

arXiv, 2022
Let $G$ be a bipartite graph with bipartition $(X,Y)$, let $k$ be a positive integer, and let $f:V(G)\rightarrow Z_k$ be a mapping with $\sum_{v\in X}f(v) \stackrel{k}{\equiv}\sum_{v\in Y}f(v)$. In this paper, we show that if $G$ is $(2m+2m_0+4k-4)$-edge-connected and $m+m_0>0$, then $G$ has an $m$-tree-connected factor $H$ such that its complement is $
arxiv