Results 161 to 170 of about 1,284,220 (297)

Functional analysis of rare genetic variants in complement factor I in advanced age-related macular degeneration. [PDF]

Hum Mol Genet, 2022
Java A, Pozzi N, Schroeder MC, Hu Z, Huan T, Seddon JM, Atkinson J.   +6 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Host immune responses to mono-infections ofPlasmodiumspp., hepatitis B virus, andMycobacterium tuberculosisas evidenced by blood complement 3, complement 5, tumor necrosis factor-α and interleukin-10

, 2018
Mathew Folaranmi Olaniyan, Tolulope Busayo Ojediran, Ferdinand Uwaifo, MufutauMosunmade Azeez   +3 more
openalex   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Rare complement factor I variants associated with reduced macular thickness and age-related macular degeneration in the UK Biobank. [PDF]

Hum Mol Genet, 2022
Tzoumas N, Kavanagh D, Cordell HJ, Lotery AJ, Patel PJ, Steel DH.   +5 more
europepmc   +1 more source

Complementation of adenovirus virus-associated RNA I gene deletion by expression of a mutant eukaryotic translation initiation factor.

, 1989
Monique V. Davies, Manohar R. Furtado, John W.B. Hershey, B. Thimmappaya, Randal J. Kaufman   +4 more
openalex   +2 more sources

Analysis of Binding Sites on Complement Factor I That Are Required for Its Activity [PDF]

, 2010
Sara C. Nilsson, Gelu M. Nita, Lisa Månsson, Tom W.L. Groeneveld, Leendert A. Trouw, Bruno O. Villoutreix, Anna M. Blom   +6 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Functional and Expressional Analyses Reveal the Distinct Role of Complement Factor I in Regulating Complement System Activation during GCRV Infection in Ctenopharyngodon idella. [PDF]

Int J Mol Sci, 2022
Liu Y, Lv Z, Xiao T, Zhang X, Ding C, Qin B, Xu B, Liu Q.   +7 more
europepmc   +1 more source