Results 171 to 180 of about 3,322,075 (363)

Peripheral complement interactions with amyloid β peptide in Alzheimer's disease: Polymorphisms, structure, and function of complement receptor 1

, 2018
Jenny U. Johansson, William D. Brubaker, Harold S. Javitz, Andrew W. Bergen, Denise Nishita, Abhishek Trigunaite, Andrés B Crane, Justine Ceballos, Diego Mastroeni, Andrea J. Tenner, Marwan N. Sabbagh, Joseph Rogers   +11 more
openalex   +2 more sources

Ontogeny of Fc receptors and complement receptor (CR3) during human myeloid differentiation. [PDF]

, 1984
Howard B. Fleit, Samuel D. Wright, C J Durie, Jay E. Valinsky, Jay C. Unkeless   +4 more
openalex   +1 more source

Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line. [PDF]

, 1984
The association between T3 and the T cell antigen receptor was examined using the T3 bearing T cell leukemic line Jurkat. A monoclonal antibody, C305, was produced, which reacted with idiotypic-like determinants expressed on Jurkat.
Stobo, JD, Weiss, A
core  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Diabetes medications with cardiovascular protection as we enter a new decade: can SGLT2 inhibitors, long-acting GLP-1 receptor agonists, pioglitazone and metformin complement each other to save lives?

, 2020
Robert E. J. Ryder, Ralph A. DeFronzo
openalex   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

A novel mouse model expressing human forms for complement receptors CR1 and CR2. [PDF]

BMC Genet, 2020
Jackson HM, Foley KE, O'Rourke R, Stearns TM, Fathalla D, Morgan BP, Howell GR.   +6 more
europepmc   +1 more source

Identification of the C3b receptor-binding domain in third component of complement.

, 1988
J. David Becherer, John D. Lambris
openalex   +1 more source

Phagocytosis via complement receptor 3 enables microbes to evade killing by neutrophils [PDF]

, 2022
Asya Smirnov, Kylene P. Daily, Mary C. Gray, Stephanie A. Ragland, Lacie M. Werner, M. Brittany Johnson, Joshua C. Eby, Erik L. Hewlett, Ronald P. Taylor, Alison K. Criss   +9 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source