Results 181 to 190 of about 193,050 (247)

Bioorthogonal tuning of nanosurface opsonisation <i>via</i> click coupling of a complement fusion protein inhibitor.

Chem Commun (Camb)
Jacques S, Gaikwad H, Pillatzke J, Moghimi SM, Simberg D.   +4 more
europepmc   +1 more source

Functional Profiling of Acetylcholine Receptor Antibodies Informs Therapeutic Outcome of FcRn Inhibitor Therapy in Myasthenia Gravis. [PDF]

Neurol Neuroimmunol Neuroinflamm
Morcone V, Morroni J, Valenzano G, Marini S, Falso S, Marini M, Habetswallner F, Farì G, Carrozza C, Iorio R.   +9 more
europepmc   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

The Role of Complement Component C5a in the Pathogenesis of Diabetic Kidney Disease: A New Kid on the Block? [PDF]

Cureus
Geladari V, Paschou E, Betsikos A, Pallas D, Sabanis N.   +4 more
europepmc   +1 more source

Dengue NS1 as a Driver of Immune-Mediated Pathogenesis. [PDF]

Trop Med Infect Dis
Wanigarathna US, Rajapakse S, Pathirana SL, Handunnetti SM, Nitsche A, Fernando N.   +5 more
europepmc   +1 more source

Modulation of NF-κB and TLR Signaling Pathways and Complement Components in Ovine Maternal Thyroid During Early Pregnancy. [PDF]

Int J Mol Sci
Zhang Y, Li J, Yang F, Wu C, Zhang L, Yang L.   +5 more
europepmc   +1 more source

Editorial: Endothelium, innate immunity and coagulation in hematological disorders. [PDF]

Front Med (Lausanne)
Evangelidis P, Gavriilaki E.
europepmc   +1 more source

Host immune responses and immune evasion mechanisms in Trypanosoma cruzi: implications for the immunopathogenesis of Chagas disease. [PDF]

Rev Soc Bras Med Trop
Andrade CMP.
europepmc   +1 more source

The Complement System in the Setting of Critical Illness-A Narrative Review. [PDF]

Biomolecules
Ampelakiotou K, Nikitopoulou I, Kokkoris S, Kotanidou A, Dimopoulou I, Detsika MG.   +5 more
europepmc   +1 more source