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Erythrocyte Complement Receptors

Critical Reviews™ in Immunology, 1995
Primate erythrocytes express complement receptors (E-CR), which can extrinsically bind C3b and Cb4. This interaction allows primate erythrocytes to bind complement opsonized particles and immune complexes, a phenomenon historically referred to as immune adherence. The binding of C3b and C4b by E-CR also leads to inhibition of complement activation. The
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The Chemistry and Biology of Complement Receptors

Springer Seminars in Immunopathology, 1984
Activation of the complement system gives rise to a number of molecular species which can interact with host-derived cells and regulate their function. This interaction is mediated through distinct cell surface complement receptors, and receptor engagement produces biologic responses which can either modulate host defense reactions or enhance ...
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Complement receptor structure and function

Immunology Today, 1985
Membrane complement receptors (CRs) are now recognized as important cell-bound components of the complement system and research into the structure and function of complement receptors is one of the main thrusts of current complement research.
G D, Ross, J P, Atkinson
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Complement Receptors in HIV Infection

Current Molecular Medicine, 2002
Similar to other pathogens, HIV can directly activate the complement pathway even in the absence of antibodies. During and after seroconversion, HIV-specific antibodies enhance the activation of complement and increase deposition of complement fragments on virions dramatically.
Susi, Doepper   +4 more
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Assays for Membrane Complement Receptors

Current Protocols in Immunology, 1994
AbstractLeukocytes express several types of receptors for activated products of the complement (C) system. This unit describes assays for a subset of these receptors: those specific for fixed fragments of C3 (CR1, CR2, CR3, and CR4). Although the assays have been designed for tests of human C receptors, they can often be carried out with rodent (e.g ...
Lynda D, O'Rear, Gordon D, Ross
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Complement Receptors in Shock and Transplantation

Archives of Surgery, 1993
Over the last decade, elegant studies of the basic biologic characteristics of inflammation and tissue injury have implicated leukocyte-mediated vascular and tissue injury in the pathogenesis of a wide variety of immune and inflammatory clinical disorders, including allograft rejection, adult respiratory distress syndrome, and shock. Recognition of the
E A, Deitch, M C, Mancini
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Complement receptors in HIV infection

Immunological Reviews, 1997
SummaryThe complement system plays an important role in the antimicrobial defense of the organism. Its components recognize a large variety of pathogens and target them for destruction, either directly by formation of a membrane attack complex or indirectly by recruiting phagocytic cells.
C, Speth, L, Kacani, M P, Dierich
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Structure and specificity of complement receptors

Immunology Letters, 1987
Fifteen to 16 cell surface proteins which interact with soluble components of the complement system have now been identified. Most of these--CR1, CR2, CR3, "CR4", DAF, HSV-1 c glycoprotein, Gp 45-70, p150,95, cell-surface Factor H, and a 90 kD protein--interact with C3 or C4 and their degradation products.
Sim, R. B.   +3 more
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Complement Receptor 2 and Autoimmunity

2003
Complement receptor 2 (CR2/CD21) plays a major role in the immune response by linking innate and adaptive immunity to foreign pathogens and proteins. In addition, several lines of evidence strongly support a role for CR2 in the maintenance of tolerance to self-antigens.
V Michael, Holers, Susan A, Boackle
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Complement Receptors and B Lymphocytes

Critical Reviews™ in Immunology, 2004
Most of the biological processes depend on cell-to-cell and protein-to-cell interactions, which take place through receptors present on the cell surface. Various physiological systems are linked by such interactions, as is the case for innate and adaptative immune response.
Marie-Bernadette, Villiers   +3 more
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