Results 11 to 20 of about 1,111,236 (286)
Engineered Trivalent Human IgG1-Fc Proteins for Potent Complement Inhibition [PDF]
CellsHigh-dose intravenous immunoglobulin (IVIG) is used to treat autoimmune and inflammatory diseases, and several studies demonstrate that the therapeutic effects of IVIG can be recapitulated with the fragment crystallizable (Fc) portion.
Ian K. Campbell +11 more
doaj +2 more sources
Neuroimmune interactions: from molecular mechanisms to therapeutic targets [PDF]
Molecular BiomedicineNeuroimmune interactions reveal that the central nervous system (CNS) is dynamically integrated with peripheral immunity. This bidirectional communication is mediated by microglia, astrocytes, peripheral immune cells, and the neurovascular unit through ...
Yi-hang Hao +3 more
doaj +2 more sources
Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors [PDF]
Cell, 2023 Manisankar Ganguly, Sudha Mishra
exaly +2 more sources
Comparative Analysis of Fcγ and Complement Receptors Presence on Monocytes in Pulmonary Sarcoidosis and Tuberculosis [PDF]
International Journal of Molecular Sciences, 2023 Piotr Trzonkowski +2 more
exaly +2 more sources
Contribution of receptors to 'Neisseria meningitidis' interactions with human macrophages [PDF]
, 2004 N. meningitidis is a gram-negative human pathogen that invades human cells, evades immune responses and goes on to cause meningococcal disease, sepsis and death.
Abdillahi, Fatumo Abdi
core +6 more sources
Non-Coding RNA, 2022 Many severe inflammation conditions are complement-dependent with the complement component C5a-C5aR1 axis as an important driver. At the RNA level, the blood transcriptome undergoes programmed expression of coding and long non-coding RNAs to combat ...
Åse Emblem +7 more
doaj +1 more source
Neutrophils Require Activation to Express Functional Cell-Surface Complement Receptor Immunoglobulin
Frontiers in Immunology, 2022 The phagocytosis-promoting complement receptor, Complement Receptor Immunoglobulin (CRIg), is exclusively expressed on macrophages. It has been demonstrated that expression in macrophages could be modulated by inflammatory mediators, including cytokines.
Annabelle G. Small +19 more
doaj +1 more source
The Role of Complement in Cancer Immunotherapy [PDF]
, 2022 The dual role of complement in both cancer development and treatment has been investigated extensively and is characterized by a substantial literature that documents the conditions in which complement can either enhance tumor growth or promote the ...
core +1 more source
Receptor-Mediated NETosis on Neutrophils
Frontiers in Immunology, 2021 Neutrophil extracellular traps (NETs), a web-like structures containing chromatin, have a significant role in assisting the capture and killing of microorganisms by neutrophils during infection.
Tao Chen +19 more
doaj +1 more source
RECEPTORS FOR COMPLEMENT ON LEUKOCYTES [PDF]
The Journal of Experimental Medicine, 1968 Sheep red blood cells sensitized by 7S, but not by 19S rabbit anti-Forssman antibodies, adhere and form rosettes on mouse macrophages and on a few monocytes and polymorphonuclear cells (PMN). When, however, C' factors from mouse serum are added to the antigen-19S antibody complex (EAC'), rosettes are formed on most mouse peritoneal macrophages and PMN ...
W H, Lay, V, Nussenzweig
openaire +2 more sources