Results 21 to 30 of about 3,229,753 (409)

Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2. [PDF]

JCI Insight, 2017
The maintenance of peripheral naive T lymphocytes in humans is dependent on their homeostatic division, not continuing emigration from the thymus, which undergoes involution with age.
Pekalski ML, García AR, Ferreira RC, Rainbow DB, Smyth DJ, Mashar M, Brady J, Savinykh N, Dopico XC, Mahmood S, Duley S, Stevens HE, Walker NM, Cutler AJ, Waldron-Lynch F, Dunger DB, Shannon-Lowe C, Coles AJ, Jones JL, Wallace C, Todd JA, Wicker LS.   +21 more
europepmc   +2 more sources

Alteration in Leukocyte Subsets and Expressions of FcγR and Complement Receptors among Female Ragpickers in Eastern India. [PDF]

Saf Health Work, 2017
Background: There are a million ragpickers in India who gather and trade recyclable municipal solid wastes materials for a living. The objective of this study was to examine whether their occupation adversely affects their immunity. Methods: Seventy-four
Mondal NK, Siddique S, Banerjee M, Roychoudhury S, Mukherjee S, Slaughter MS, Lahiri T, Ray MR.   +7 more
europepmc   +2 more sources

Receptor-Mediated NETosis on Neutrophils

Frontiers in Immunology, 2021
Neutrophil extracellular traps (NETs), a web-like structures containing chromatin, have a significant role in assisting the capture and killing of microorganisms by neutrophils during infection.
Tao Chen, Tao Chen, Tao Chen, Yanhong Li, Yanhong Li, Yanhong Li, Rui Sun, Rui Sun, Rui Sun, Huifang Hu, Huifang Hu, Huifang Hu, Yi Liu, Yi Liu, Yi Liu, Martin Herrmann, Yi Zhao, Yi Zhao, Yi Zhao, Luis E. Muñoz   +19 more
doaj   +1 more source

Neutrophils Require Activation to Express Functional Cell-Surface Complement Receptor Immunoglobulin

Frontiers in Immunology, 2022
The phagocytosis-promoting complement receptor, Complement Receptor Immunoglobulin (CRIg), is exclusively expressed on macrophages. It has been demonstrated that expression in macrophages could be modulated by inflammatory mediators, including cytokines.
Annabelle G. Small, Annabelle G. Small, Annabelle G. Small, Annabelle G. Small, Khalida Perveen, Khalida Perveen, Trishni Putty, Trishni Putty, Nikita Patel, Nikita Patel, Patrick Quinn, Patrick Quinn, Mihir D. Wechalekar, Charles S. Hii, Charles S. Hii, Alex Quach, Alex Quach, Antonio Ferrante, Antonio Ferrante, Antonio Ferrante   +19 more
doaj   +1 more source

Mathematical Characterization of Private and Public Immune Repertoire Sequences [PDF]

Bull Math Biol 85, 102 (2023), 2022
Diverse T and B cell repertoires play an important role in mounting effective immune responses against a wide range of pathogens and malignant cells. The number of unique T and B cell clones is characterized by T and B cell receptors (TCRs and BCRs), respectively.
arxiv   +1 more source

Blood Transcriptome Analysis of Septic Patients Reveals a Long Non-Coding Alu-RNA in the Complement C5a Receptor 1 Gene

Non-Coding RNA, 2022
Many severe inflammation conditions are complement-dependent with the complement component C5a-C5aR1 axis as an important driver. At the RNA level, the blood transcriptome undergoes programmed expression of coding and long non-coding RNAs to combat ...
Åse Emblem, Erik Knutsen, Tor Erik Jørgensen, Hilde Fure, Steinar Daae Johansen, Ole-Lars Brekke, Tom Eirik Mollnes, Bård Ove Karlsen   +7 more
doaj   +1 more source

Utilization of complement receptors in immune cell - microbe interaction.

FEBS Letters, 2020
The complement system is a major humoral component of immunity and is essential for the fast elimination of pathogens invading the body. In addition to its indispensable role in innate immunity, the complement system is also involved in pathogen ...
Szilvia Lukácsi, Bernadett Mácsik-Valent, Zsuzsa Nagy-Baló, Kristóf G. Kovács, Kristóf Kliment, Z. Bajtay, A. Erdei   +6 more
semanticscholar   +1 more source

The Role of Complement in the Mechanism of Action of Therapeutic Anti-Cancer mAbs

Antibodies, 2020
Unconjugated anti-cancer IgG1 monoclonal antibodies (mAbs) activate antibody-dependent cellular cytotoxicity (ADCC) by natural killer (NK) cells and antibody-dependent cellular phagocytosis (ADCP) by macrophages, and these activities are thought to be ...
Josée Golay, Ronald P. Taylor
doaj   +1 more source

C3‐dependent effector functions of complement

Immunological Reviews, 2022
C3 is the central effector molecule of the complement system, mediating its multiple functions through different binding sites and their corresponding receptors. We will introduce the C3 forms (native C3, C3 [H2O], and intracellular C3), the C3 fragments
A. Zarantonello, Margot Revel, Anne Grunenwald, L. Roumenina   +3 more
semanticscholar   +1 more source

Tetracycline as an inhibitor to the coronavirus SARS-CoV-2 [PDF]

J Cell Biochem (2021) 1-8, 2020
The coronavirus SARS-CoV-2 remains an extant threat against public health on a global scale. Cell infection begins when the spike protein of SARS-CoV-2 binds with the cell receptor, angiotensin-converting enzyme 2 (ACE2). Here, we address the role of Tetracycline as an inhibitor for the receptor-binding domain (RBD) of the spike protein.
arxiv   +1 more source