Results 41 to 50 of about 3,229,753 (409)
Revising Berg-Purcell for finite receptor kinetics [PDF]
, 2021 From nutrient uptake, to chemoreception, to synaptic transmission, many systems in cell biology depend on molecules diffusing and binding to membrane receptors. Mathematical analysis of such systems often neglects the fact that receptors process molecules at finite kinetic rates.
arxiv +1 more source
Complement Proteins as Soluble Pattern Recognition Receptors for Pathogenic Viruses
Viruses, 2021 The complement system represents a crucial part of innate immunity. It contains a diverse range of soluble activators, membrane-bound receptors, and regulators.
Valarmathy Murugaiah +5 more
doaj +1 more source
Ischemia and reperfusion injury in kidney transplantation : relevant mechanisms in injury and repair [PDF]
, 2020 Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation.
Berger, Stefan P. +7 more
core +2 more sources
Neutrophil chemoattractant receptors in health and disease: double-edged swords
Cellular & Molecular Immunology, 2020 Neutrophils are frontline cells of the innate immune system. These effector leukocytes are equipped with intriguing antimicrobial machinery and consequently display high cytotoxic potential. Accurate neutrophil recruitment is essential to combat microbes
Mieke Metzemaekers, M. Gouwy, P. Proost
semanticscholar +1 more source
Role of Complement and Histones in Sepsis
Frontiers in Medicine, 2020 The wide use of the mouse model of polymicrobial sepsis has provided important evidence for events occurring in infectious sepsis involving septic mice and septic humans.
Firas S. Zetoune, Peter A. Ward
doaj +1 more source
Modulation of granulocyte LAM-1 and MAC-1 during dialysis—A prospective, randomized controlled trial [PDF]
, 1992 Modulation of granulocyte LAM-1 and MAC-1 during dialysis—A prospective, randomized controlled trial. Hemodialysis with first-use cellulosic dialysis membranes results in activation of the alternative pathway of complement and profound neutropenia ...
Hakim, Raymond +3 more
core +1 more source
PLoS ONE, 2012 Early complement components are important for normal antibody responses. In this process, complement receptors 1 and 2 (CR1/2), expressed on B cells and follicular dendritic cells (FDCs) in mice, play a central role.
Christian Rutemark +5 more
semanticscholar +1 more source
Direct imaging of lateral movements of AMPA receptors inside synapses [PDF]
EMBO J 22, 18 (15/09/2003) 4656-65, 2007 Trafficking of AMPA receptors in and out of synapses is crucial for synaptic plasticity. Previous studies have focused on the role of endo/exocytosis processes or that of lateral diffusion of extra-synaptic receptors. We have now directly imaged AMPAR movements inside and outside synapses of live neurons using single-molecule fluorescence microscopy ...
arxiv +1 more source
Complement and its receptors: new insights into human disease.
Annual Review of Immunology, 2014 Although new activation and regulatory mechanisms are still being identified, the basic architecture of the complement system has been known for decades.
V. Holers
semanticscholar +1 more source
Anaphylatoxins spark the flame in early autoimmunity
Frontiers in Immunology, 2022 The complement system (CS) is an ancient and highly conserved part of the innate immune system with important functions in immune defense. The multiple fragments bind to specific receptors on innate and adaptive immune cells, the activation of which ...
Jovan Schanzenbacher +3 more
doaj +1 more source