Results 111 to 120 of about 140,468 (298)

Assessment of the interaction of human complement regulatory proteins with group AStreptococcus. Identification of a high-affinity group AStreptococcus binding site in FHL-1 [PDF]

, 2000
David Pérez-Caballero, Sebastián Albertí, Fernando Vivanco, Pilar Sánchez‐Corral, Santiago Rodrı́guez de Córdoba   +4 more
openalex   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Crry/p65, a Membrane Complement Regulatory Protein, Has Costimulatory Properties on Mouse T Cells [PDF]

, 2000
Elena Fernández-Centeno, Gloria Ojeda, José María Rojo, Pilàr Portolés   +3 more
openalex   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

GluR3 Autoantibodies Destroy Neural Cells in a Complement-Dependent Manner Modulated by Complement Regulatory Proteins [PDF]

, 2000
Karl Whitney, James O McNamara
openalex   +1 more source

GDP‐fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP‐fucose and fucosylated glycan synthesis

FEBS Open Bio, EarlyView.
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley   +1 more source

Clinical values of serum Gd-IgA1， complement factor H and complement regulatory proteins in IgA nephropathy

Linchuang shenzangbing zazhi
ObjectiveTo explore the diagnostic values of serum galactose-deficient IgA1（Gd-IgA1）， C4， complement factor H（CFH） and complement factor H-related protein （CFHRP） 1， 3， 5 in IgA nephropathy（IgAN）.MethodsA total of 58 patients with primary IgAN diagnosed ...
Zou Mei, Xue Hen, Lu Fang-cao, Zheng Guang-yi, Zhao Min   +4 more
doaj  

Challenges in classification of novel CFH variants in patients with atypical hemolytic uremic syndrome

Thrombosis Update, 2020
Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA) characterized by dysregulation of the alternative pathway of complement. Heterozygous variants in complement and complement regulatory proteins may increase risk for aHUS and,
Meera Sridharan, Michelle L. Kluge, Ronald S. Go, Roshini S. Abraham, Ann M. Moyer   +4 more
doaj  

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Cd47-Signal Regulatory Protein α (Sirpα) Regulates Fcγ and Complement Receptor–Mediated Phagocytosis [PDF]

, 2001
Per‐Arne Oldenborg, Hattie D. Gresham, Frederik P. Lindberg   +2 more
openalex   +1 more source