Results 161 to 170 of about 172,719 (244)
C3 glomerulopathy in transplant "like yet unlike native": Pathophysiology, recent advances in therapeutics and evolving paradigms. [PDF]
Chutani A, Norouzi S, Lerma EV.
europepmc +1 more source
One‐Step Curcumin‐Mediated Multiphoton Lithography for Bioactive 3D Scaffolds
Curcumin‐mediated multiphoton lithography enables one‐step fabrication of highly architected complex gelatin methacryloyl scaffolds by exploiting curcumin as a multifunctional bioactive photoinitiator. The resulting 3D structures support mesenchymal stem cell adhesion, proliferation, and migration, while exhibiting dual antibacterial activity through ...
Myrto Charitaki +7 more
wiley +1 more source
Decoding the Factor H-Related Proteins: Gatekeepers of Complement Dysregulation in AMD. [PDF]
Tang J, Zgoda N, Clark SJ.
europepmc +1 more source
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang +7 more
wiley +1 more source
A new perspective on AMD pathogenesis: a sequential Factor H-centered view of complement dysregulation. [PDF]
Skerka C +9 more
europepmc +1 more source
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Shifting From Systemic to Precision-Targeted Complement Therapies: Opportunities and Hurdles. [PDF]
Mannes M, Zelek WM, Trouw LA.
europepmc +1 more source
A migration‐permissive bioink composed of methacrylated collagen type I and thiolated hyaluronic acid enables 3D bioprinting of breast cancer‐stroma models. Single‐cell tracking reveals that adipose stromal cells enhance tumor cell motility and stromal invasion, accompanied by collagen remodeling, and a shift in tumor cell morphology.
Sabrina Stecher +19 more
wiley +1 more source
The complement system in Alzheimer's disease: mechanisms, biomarkers, and therapeutic implications. [PDF]
Liu G +12 more
europepmc +1 more source

