Results 191 to 200 of about 140,468 (298)

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Incorporation of host complement regulatory proteins into Newcastle disease virus enhances complement evasion. [PDF]

J Virol, 2012
Biswas M, Johnson JB, Kumar SR, Parks GD, Elankumarana S.   +4 more
europepmc   +1 more source

Semiconducting Polymer Nanoparticles as Multimodal Agents for Optical and Magnetic Resonance Imaging

Advanced Healthcare Materials, EarlyView.
Semiconducting polymer nanoparticles (SPNs) exhibit many advantageous optical and biological properties. Multimodal SPN‐based contrast agents that integrate several imaging modalities yield a wealth of information through the use of different imaging mechanisms.
Faysal A. Farah, Yu Qin, Mark A. Green, James D. E. T. Wilton‐Ely   +3 more
wiley   +1 more source

The 'autoimmunome' of centenarians. [PDF]

J Transl Autoimmun
Carrera-Bastos P, Plaza-Florido A, Santos-Lozano A, Borba V, Rodríguez-Romo G, García-Chico C, Lista S, Saco-Ledo G, Emanuele E, Shoenfeld Y, Lucia A.   +10 more
europepmc   +1 more source

Advanced Oral Delivery Systems for Nutraceuticals

Advanced Healthcare Materials, EarlyView.
Emerging delivery technologies are explored to overcome barriers to oral nutraceutical absorption. Traditional carriers are compared with novel platforms including biodegradable polymers, MOFs, MPNs, and 3D printing. These systems enhance bioavailability, control release, and enable personalized nutrition.
Xin Yang, Linzixuan Zhang, Zhiling Zheng, Robert Langer, Ana Jaklenec   +4 more
wiley   +1 more source

Correction: Complement activity and autophagy are dysregulated in the lungs of patients with nonresolvable COVID‑19 requiring lung transplantation. [PDF]

Respir Res
Shivshankar P, Mueller-Ortiz SL, Domozhirov AY, Bi W, Collum SD, Doursout MF, Patel M, LeFebvre IN, Akkanti B, Yau S, Huang HJ, Hussain R, Karmouty-Quintana H.   +12 more
europepmc   +1 more source

A Novel Monoclonal Antibody against FbaA Can Inhibit the Binding of the Complement Regulatory Protein Factor H to Group A Streptococcus

, 2011
Cuiqing Ma, Yiyang Guo, GU Hai-yan, Ling Zhang, Hainan Liu, Huidong Feng, Lin Wei   +6 more
openalex   +1 more source

RBC Membrane‐Camouflaged Nanosystem‐Mediated Synergistic Drug Combination for Enhanced Anti‐Tumor Therapy

Advanced Healthcare Materials, EarlyView.
An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng, Xuemei Zhong, Lu Deng, Xinling He, Miaoxizi Luo, Ruibing Wang, Jinming Zhang   +6 more
wiley   +1 more source

Thrombospondin-1 inhibits alternative complement pathway activation in antineutrophil cytoplasmic antibody-associated vasculitis. [PDF]

J Clin Invest
Konwar S, Schroda S, Rogg M, Kleindienst J, Decker EL, Pohl M, Zieger B, Panse J, Wang H, Grosse R, Schell C, Vidal S, Liu X, Gorzelanny C, Tschongov T, Häffner K.   +15 more
europepmc   +1 more source

104 MEMBRANE-BOUND COMPLEMENT REGULATORY PROTEIN EXPRESSION DECREASES IN SYNOVIUM DURING OA PROGRESSION AND IS ASSOCIATED WITH INCREASED C5B-9 DEPOSITION

, 2011
JA Scott, Carla R. Scanzello, Mary K. Crow   +2 more
openalex   +1 more source