Results 211 to 220 of about 172,719 (244)
Some of the next articles are maybe not open access.
European Journal of Cardio-Thoracic Surgery, 1993
Cardiopulmonary bypass-induced organ dysfunction remains a clinical problem in certain groups of patients. Although the pathogenesis is multifactorial, it is likely that a panendothelial injury consequent upon widespread humoral and cellular activation is a major contributor to this process. The biologically active products of complement activation are
N E, Moat, D F, Shore, T W, Evans
openaire +2 more sources
Cardiopulmonary bypass-induced organ dysfunction remains a clinical problem in certain groups of patients. Although the pathogenesis is multifactorial, it is likely that a panendothelial injury consequent upon widespread humoral and cellular activation is a major contributor to this process. The biologically active products of complement activation are
N E, Moat, D F, Shore, T W, Evans
openaire +2 more sources
The role of complement protein and complement regulatory protein in diabetic nephropathy
Human ImmunologyDiabetic nephropathy is one of the main causes of end-stage renal disease, with dysregulation of the complement system playing a critical role in its pathogenesis. However, the specific mechanisms, key effector molecules, and relevant therapeutic targets still require further investigation.This review involves searching databases such as PubMed and Web
Xiaoxiang Jiang, Zhanzhan Sun
openaire +2 more sources
C4b-Binding protein, a regulatory protein of complement
Immunologic Research, 1991Despite the wealth of structural and functional information on C4BP, it is clear that several aspects of C4BP biology and regulation under normal conditions and in the acute-phase response remain unresolved. Studies to identify which interleukin and cytokines regulate C4BP expression (both α-and β-chains) are underway in our laboratory.
openaire +2 more sources
Structure-Function Relationships of the Complement Regulatory Protein, CD59
Blood Cells, Molecules, and Diseases, 1996CD59 (membrane inhibitor of reactive lysis, protectin) is a membrane protein whose functions include the inhibition of the insertion of the ninth component of complement into the target membrane. It belongs to a superfamily of proteins including Ly-6, elapid snake venom toxins, and urokinase receptor (UPAR); the members of the superfamily have a ...
J, Petranka +6 more
openaire +2 more sources
The expression of complement regulatory proteins by adult human oligodendrocytes
Journal of Neuroimmunology, 1998In multiple sclerosis, infiltrating T lymphocytes and perivascular microglia may initiate demyelinating lesions, but a role for antibody and complement in the ensuing inflammatory damage to myelin and oligodendrocytes is likely. In most tissues, ubiquitously expressed complement regulatory proteins prevent autologous destruction, protecting host cells ...
N J, Scolding +2 more
openaire +2 more sources
Expression of complement regulatory proteins in the developing human kidney
Pediatric Nephrology, 2000Complement homologous restriction factor CD59 and complement receptor CD35 are typically involved in the regulation of the host defense system. Recent observations in the human fetal kidney suggest a further role for complement cell surface regulators CD35 and CD59 in kidney development and maturation.
D J, Bridgewater, A, Mok, D G, Matsell
openaire +2 more sources
The Role of Membrane Complement Regulatory Proteins in Cancer Immunotherapy
2008Anti-tumor monoclonal antibody therapy represents one of the earliest targeted therapies in clinical cancer care and has achieved great clinical promise. Complement activation mediated by anti-tumor mAbs can result in direct tumor lysis or enhancement of antibody-dependent cellular cytotoxicy.
Jun, Yan +5 more
openaire +4 more sources
Antibodies to complement regulatory proteins
Transfusion Clinique et Biologique, 1997G, Daniels, C, Green, A, Petty
openaire +2 more sources
Coordinator's report: complement regulatory proteins
Transfusion Clinique et Biologique, 1997J M, Moulds +6 more
openaire +2 more sources
Insights into the role of complement regulatory proteins in HPV mediated cervical carcinogenesis
Seminars in Cancer Biology, 2022Ajit Kumar Passari +2 more
exaly