Results 91 to 100 of about 24,757,633 (403)

An “Outside-In” and “Inside-Out” Consideration of Complement in the Multiple Sclerosis Brain: Lessons From Development and Neurodegenerative Diseases

open access: yesFrontiers in Cellular Neuroscience, 2021
The last 15 years have seen an explosion of new findings on the role of complement, a major arm of the immune system, in the central nervous system (CNS) compartment including contributions to cell migration, elimination of synapse during development ...
B. Paul Morgan   +2 more
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Significance of Complement System in Ischemic Stroke: A Comprehensive Review

open access: yesAging and Disease, 2019
The complement system is an essential part of innate immunity, typically conferring protection via eliminating pathogens and accumulating debris.
Yuanyuan Ma   +3 more
semanticscholar   +1 more source

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Complement System Part II: Role in Immunity

open access: yesFrontiers in Immunology, 2015
The complement system has been considered for a long time as a simple lytic cascade, aimed to kill bacteria infecting the host organism. Nowadays, this vision has changed and it is well accepted that complement is a complex innate immune surveillance ...
N. Merle   +4 more
semanticscholar   +1 more source

Coherent states and global entanglement in an N qubit system

open access: yes, 2007
We consider an $N$ qubit system and show that in the symmetric subspace, $\mathbb{S}$ a state is not globally entangled, iff it is a coherent state.
Ali   +23 more
core   +1 more source

Tautological systems and free divisors [PDF]

open access: yes, 2019
We introduce tautological system defined by prehomogenous actions of reductive algebraic groups. If the complement of the open orbit is a linear free divisor satisfying a certain finiteness condition, we show that these systems underly mixed Hodge ...
Macarro, Luis Narváez   +1 more
core   +2 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Oka properties of complements of holomorphically convex sets [PDF]

open access: yesarXiv, 2020
Our main theorem states that the complement of a compact holomorphically convex set in a Stein manifold with the density property is an Oka manifold. This gives a positive answer to the well-known long-standing problem in Oka theory whether the complement of a compact polynomially convex set in $\mathbb{C}^{n}$ $(n>1)$ is Oka.
arxiv  

Cohomology of $\mathbb{Z}$-local systems on complex hyperplane arrangement complements [PDF]

open access: yesarXiv, 2022
We prove a Cohen-Dimca-Orlik type theorem for rank one $\mathbb{Z}$-local systems on complex hyperplane arrangement complements. This settles a recent conjecture of S. Sugawara.
arxiv  

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