Results 61 to 70 of about 24,198,541 (380)
Frontiers in Immunology, 2023 Primary complement system (C) deficiencies are rare but notably associated with an increased risk of infections, autoimmunity, or immune disorders.
Andrea Balduit +13 more
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Marked central nervous system pathology in CD59 knockout rats following passive transfer of Neuromyelitis optica immunoglobulin G. [PDF]
, 2017 Neuromyelitis optica spectrum disorders (herein called NMO) is an inflammatory demyelinating disease of the central nervous system in which pathogenesis involves complement-dependent cytotoxicity (CDC) produced by immunoglobulin G autoantibodies ...
Verkman, Alan S, Yao, Xiaoming
core +2 more sources
Pitfalls in complement analysis: A systematic literature review of assessing complement activation
Frontiers in Immunology, 2022 BackgroundThe complement system is an essential component of our innate defense and plays a vital role in the pathogenesis of many diseases. Assessment of complement activation is critical in monitoring both disease progression and response to therapy ...
Ricardo J. M. G. E. Brandwijk +8 more
doaj +1 more source
The interaction between the complement system and hemostatic factors.
Current opinion in hematology, 2020 PURPOSE OF REVIEW To discuss the crosstalk between the complement system and hemostatic factors (coagulation cascade, platelet, endothelium, and Von Willebrand Factor), and the consequences of this interaction under physiologic and pathologic conditions.
S. Oncul, V. Afshar-Kharghan
semanticscholar +1 more source
On the Modulation Equations and Stability of Periodic GKdV Waves via Bloch Decompositions [PDF]
, 2010 In this paper, we complement recent results of Bronski and Johnson and of Johnson and Zumbrun concerning the modulational stability of spatially periodic traveling wave solutions of the generalized Korteweg-de Vries equation. In this previous work it was
Bampi +33 more
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Frontiers in Immunology, 2020 Preeclampsia is one of the leading causes of maternal and neonatal mortality and morbidity worldwide, affecting 2–8% of all pregnancies. Studies suggest a link between complement activation and preeclampsia.
E. Pierik +6 more
doaj +1 more source
Journal of Neuroinflammation, 2021 Background Synucleinopathies are characterized by neurodegeneration and deposition of the presynaptic protein α-synuclein in pathological protein inclusions.
Emil Gregersen +7 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2021 As part of the innate immune system, complement plays a critical role in the elimination of pathogens and mobilization of cellular immune responses. In the central nervous system (CNS), many complement proteins are locally produced and regulate nervous ...
Noriko Shinjyo +4 more
doaj +1 more source
Frontiers in Immunology, 2020 The complement system is an important part of the innate immune system, providing a strong defense against pathogens and removing apoptotic cells and immune complexes.
Esther C. W. de Boer +4 more
doaj +1 more source
International Journal of Immunopathology and Pharmacology, 1992 The human complement system (C) acts to lyse susceptible cells, to promote phagocytosis of target particles, and to solubilize immune-complexes, its activation generates peptides that mediate features of the inflammatory response. It is comprised of a series of plasma zymogens, activated by proteolytic cleavage in a cascade manner, and of plasma and ...
Angelo Agostoni +3 more
openaire +2 more sources