Results 81 to 90 of about 1,195,438 (288)
Exploration of ImmunologyThe complement system is a key component of the innate immune system that mediates the clearance of pathogens, apoptotic cells, and cellular debris.
Jeyaparthasarathy Narayanaperumal +1 more
doaj +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
The Complement System in Dialysis: A Forgotten Story?
Frontiers in Immunology, 2018 Significant advances have lead to a greater understanding of the role of the complement system within nephrology. The success of the first clinically approved complement inhibitor has created renewed appreciation of complement-targeting therapeutics ...
Felix Poppelaars +10 more
doaj +1 more source
A nested Schur complement solver with mesh-independent convergence for the time domain photonics modeling [PDF]
arXiv, 2019 A nested Schur complement solver is proposed for iterative solution of linear systems arising in exponential and implicit time integration of the Maxwell equations with perfectly matched layer (PML) nonreflecting boundary conditions. These linear systems are the so-called double saddle point systems whose structure is handled by the Schur complement ...
arxiv
Molecular Oncology, EarlyView.Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim +8 more
wiley +1 more source
A Kuratowski closure-complement variant whose solution is independent of ZF [PDF]
arXiv, 2020 We pose the following new variant of the Kuratowski closure-complement problem: How many distinct sets may be obtained by starting with a set $A$ of a Polish space $X$, and applying only closure, complementation, and the $d$ operator, as often as desired, in any order?
arxiv
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source
Resonant local systems on complements of discriminantal arrangements and sl_2 representations [PDF]
Geom. Dedicata 101 (2003), 217-234, 2002 We calculate the skew-symmetric cohomology of the complement of a discriminantal hyperplane arrangement with coefficients in local systems arising in the context of the representation theory of the Lie algebra sl_2. For a discriminantal arrangement in C^k, the skew-symmetric cohomology is nontrivial in dimension k-1 precisely when the "master function"
arxiv
Experiments with the Cyprus strain of blue-tongue virus: multiplication in the central nervous system of mice and complement fixation [PDF]
, 1954 M. Van Den Ende +2 more
openalex +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source