Cartilage oligomeric matrix protein-induced complement activation in systemic sclerosis [PDF]
Arthritis Research & Therapy, 2013 Abstract Introduction Complexes between cartilage oligomeric matrix protein (COMP) and the complement activation product C3b have been found in the circulation of patients with rheumatoid arthritis and systemic lupus erythematosus.
Otteby, Kaisa E +5 more
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Complement activation and protein adsorption by carbon nanotubes [PDF]
, 2006 As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored.
Flahaut, Emmanuel +5 more
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The tumour microenvironment links complement system dysregulation and hypoxic signalling. [PDF]
, 2018 The complement system is an innate immune pathway typically thought of as part of the first line of defence against "non-self" species. In the context of cancer, complement has been described to have an active role in facilitating cancer-associated ...
Giaccia, Amato J +4 more
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INTERACTIONS OF C-REACTIVE PROTEIN WITH THE COMPLEMENT SYSTEM [PDF]
The Journal of Experimental Medicine, 1974 Protamine sulfate was found to consume large amounts of C selectively during preincubation with sera of individuals in the "acute phase". Marked depletion of C1, C4, and C2 with minimal, if any, depletion of C3-9, was observed. The consumption was time and temperature dependent, occurring most rapidly and extensively at 37°C, 0.10 M relative salt ...
Joan Siegel +2 more
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Local Activation of the Alternative Pathway of Complement System in Mycotic Keratitis Patient Tear
Frontiers in Cellular and Infection Microbiology, 2020 Aspergillus flavus and Fusarium solani are the predominant causative agents of mycotic keratitis in the tropical part of the world. Tear proteins play a major role in the innate immune response against these fungal infections as has been shown by the ...
Mohammed Razeeth Shait Mohammed +6 more
doaj +1 more source
Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system [PDF]
, 2016 Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV) infection. The mechanism of HCV-related lymphoproliferative disorders is not fully understood.
Alter, Harvey J. +7 more
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Complement Fixation in the C-reactive Protein System
Experimental Biology and Medicine, 1954 SummaryA complement fixation method based on the reaction between CRP in human test sera and rabbit CRP antisera has been described.
L H, MUSCHEL, R J, WEATHERWAX
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Complement Evasion: An Effective Strategy That Parasites Utilize to Survive in the Host
Frontiers in Microbiology, 2019 Parasitic infections induce host immune responses that eliminate the invading parasites. However, parasites have evolved to develop many strategies to evade host immune attacks and survive in a hostile environment. The complement system acts as the first
Shuai Shao +4 more
doaj +1 more source
A novel trifunctional IgG-like bispecific antibody to inhibit HIV-1 infection and enhance lysis of HIV by targeting activation of complement [PDF]
, 2010 BACKGROUND: The complement system is not only a key component of innate immunity but also provides a first line of defense against invading pathogens, especially for viral pathogens.
Chuanfu Zhang +14 more
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Frontiers in Immunology, 2022 The complement system is a part of the innate immune system, where it labels intruding pathogens as well as dying host cells for clearance. If complement regulation is compromised, the system may contribute to pathogenesis.
Henrik Pedersen +7 more
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