Results 151 to 160 of about 898,423 (293)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Role of CIA2 and CIL in the Regulation of Chloroplast Development During Photomorphogenesis in Arabidopsis. [PDF]

Cells
Zarrin Ghalami R, Burdiak P, Kamran M, Duszyn M, Rusaczonek A, Muszyńska E, Karpiński S.   +6 more
europepmc   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Generation of exogenous kidneys via CRISPR/Cas9 mediated blastocyst complementation targeting Osr1 gene in mice. [PDF]

Sci Rep
Yeh TY, Chiu IM, Huang YJ, Wu SC, Hsieh CC, Sung HH, Hwu WL, Wang GJ, Ju JC.   +8 more
europepmc   +1 more source

Generation of kidney from pluripotent stem cells via blastocyst complementation.

American Journal of Pathology, 2012
Jo-ichi Usui, Toshihiro Kobayashi, Tomoyuki Yamaguchi, A. Knisely, R. Nishinakamura, H. Nakauchi   +5 more
semanticscholar   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

The critical role of <i>hcpR</i> in regulating nitrosative stress defense in <i>Clostridioides difficile</i>. [PDF]

Appl Environ Microbiol
Kalra S, Ayinde TO, Olaitan AO.
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

A signaling pathway mediating abscisic acid-induced jasmonic acid biosynthesis during strawberry ripening. [PDF]

J Integr Plant Biol
Jia K, Zeng B, Dai Z, Zhang X, Wang J, Wu C, Feng C, Yan G, Zhang K, Duan X, Wang W.   +10 more
europepmc   +1 more source

Visualization of molecular interactions by fluorescence complementation

Nature reviews. Molecular cell biology, 2006
T. Kerppola
semanticscholar   +1 more source