In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo +6 more
wiley +1 more source
Isolation and complete genome sequence analysis of an Echovirus 29 strain isolated from a patient of Acute Flaccid Paralysis in India. [PDF]
Joshi MS +8 more
europepmc +1 more source
This study demonstrates that HDAC1/2 knockout in microglia alleviates neurological deficits, preserves white matter, and accelerates hematoma clearance after ICH. HDAC1/2 inhibition reduces HK2 acetylation, shifts metabolism from glycolysis to fatty acid oxidation, reduces inflammation, and enhances phagocytosis.
Zhiwen Jiang +9 more
wiley +1 more source
Complete genome sequence of <i>Metarhizium marquandii</i> strain ISA501. [PDF]
Zhou J +4 more
europepmc +1 more source
Complete genome sequence of <i>Serratia marcescens</i> MPHSM1, isolated from a patient with necrotizing fasciitis. [PDF]
Mamiya M +6 more
europepmc +1 more source
Complete genome sequence of a <i>Capillovirus</i> infecting <i>Citrus medica</i> L. in China. [PDF]
Wang Y +7 more
europepmc +1 more source
Complete genome sequence of SARS-CoV-2 isolated from a dog in Kazakhstan. [PDF]
Nurpeisova A +25 more
europepmc +1 more source
Complete genome sequence of a <i>Desulfovibrio legallii</i> clinical isolate, GTC18478, from Japan. [PDF]
Hayashi M +5 more
europepmc +1 more source
Complete genome sequence of vB_PaBD_211, a lytic <i>Pseudomonas aeruginosa</i> phage isolated from poultry sewage in Bangladesh. [PDF]
Sarkar M, Anik TA, Ahmed S.
europepmc +1 more source

