Results 221 to 230 of about 616,916 (268)

Complete Genome Sequence of two <i>Gordonia rubripertincta</i> cluster CS4 Bacteriophages, Vitaenoii and Philon9. [PDF]

MicroPubl Biol
McMenemy JT, Acra AI, Alexander EA, Cordovez VK, Fitzpatrick MM, Mejia D, Smith CH, Fogarty MP.   +7 more
europepmc   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source

Characterization of the first complete genome sequence of yellow fever virus (YFV) in Sierra Leone: Implications for public health. [PDF]

PLoS Negl Trop Dis
Sandi JD, Brock-Fisher TM, Kallon TMPS, Paye MF, Fofanah IU, Nosamiefan D, Kamara MS, Teh AJ, Turay A, Wilkason C, Baudi I, Tomkins-Tinch C, I'Anson C, Stachler E, Pekar JE, Ozonoff A, Park D, Happi C, Sabeti PC, Grant DS.   +19 more
europepmc   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

The complete genome sequence of the Acestrorhamphid <i>Psalidodon fasciatus</i>. [PDF]

Biodivers Genomes
De la Ossa-Guerra LE, Pirro S, Artoni RF, Berbel-Filho WM.   +3 more
europepmc   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Complete genome sequence of Streptococcus periodonticum strain CRC221 isolated from human colorectal tumor tissue. [PDF]

BMC Genom Data
Li JS, Chen SD, Wu JQ, Gao MX, Li ZS, Du YQ, Hou WL.   +6 more
europepmc   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Complete genome sequence of Oscillospiraceae bacterium MB24-C1, isolated from sewage sludge. [PDF]

Microbiol Resour Announc
Zhao J, Qiu W, Li F, Dong G, Li Y, Shih C-J, Wu Y-C, Wu C-H, Lai S-J, Xiao W, Zhang W-L, Li N, Chen S-C.   +12 more
europepmc   +1 more source