Results 101 to 110 of about 995,298 (311)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Software component certification
, 2001 A model for software component certification based on test certificates supplied by developers in a standard portable form is proposed. Purchasers are expected to use the model to determine the quality and suitability of purchased software.
Morris, J. +4 more
core
Integration of Extra-Functional Properties in Component Models
, 2009 Management of extra-functional properties in component models is one ofthe main challenges in the component-based software engineering community.Still, the starting point in their management, namely their specification in acontext of component models is ...
Ivica Crnković +7 more
core +1 more source
Algebraic specifications and refinement for component-based development using RAISE
Journal of Computer Science and Technology, 2002 There are two main activities in Component-Based Development: component development, where we build libraries for general use, and component integration, where we assemble an application from existing components.
Elsa Clara Estévez +1 more
doaj
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Assessing real-time component contracts through built-in evolutionary testing
, 2022 S.107-122 : Ill., Lit.Real-time contracts between components, as an important aspect of quality-of-service considerations, add a new dimension to the development and validation of component-based embedded systems.
Groß, H.-G., Mayer, N., Riano, J.P.
core
Process Patterns for Component-Based Software Development
, 2009 Component-Based Development (CBD) has been broadly used in software development, as it enhances reusability and flexibility, and reduces the costs and risks involved in systems development. It has therefore spawned many widely-used approaches, such as Commercial Off-The-Shelf (COTS) and software product lines.
Ehsan Kouroshfar +2 more
openaire +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Component-oriented approaches for software development in the extreme-scale computing era
, 2011 The complexity of high-end computing has been increasing rapidly following the exponential increase in processing speed of the novel electronic digital technologies. Subsequently, the software development productivity has been attracting higher attention
Getov, Vladimir
core +1 more source