Results 71 to 80 of about 3,111,469 (297)

The prevalence of computer game addiction and related factors in male adolescent of Gonabad in 2018

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2020
Background and Aim: Computer games are a kind of growing and attractive new communication technology. This has prompted researchers to study the effects of these games on users.
Mitra Moodi   +2 more
doaj  

Virtuella lekkamrater

open access: yesKulturella Perspektiv, 1996
Do computer games constitute something new in the world of children? Yes, there are certain elements in computer games, both as phenomenon and in their contents, that make them unique to our times and that interact with tendencies in the rest of our ...
Barbro Johansson
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

‘Grand Theft Archive’: A Quantitative Analysis of the State of Computer Game Preservation

open access: yesInternational Journal of Digital Curation, 2008
Computer games, like other digital media, are extremely vulnerable to long-term loss, yet little work has been done to preserve them. As a result we are experiencing large-scale loss of the early years of gaming history.
Paul Gooding, Melissa Terras
doaj   +3 more sources

GAMING COMPUTER ENTHUSIASM AS A PREDICTOR OF ADOLESCENT BULLYING

open access: yesВестник Мининского университета, 2017
Introduction: In the era of intensive computerization of society, the computer becomes an integral part of the life of a modern teenager. The virtual world contributes to the formation and development of those forms of individuality, which are largely ...
A. V. Grishina, E. N. Volkova
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

A conceptual framework for serious games and its validation

open access: yes, 2010
This research introduces a conceptual framework for the design of serious games and uses the Technology Acceptance Model (TAM) for its validation.
Yusoff, Amri
core   +1 more source

Faderen som helt i computerspil

open access: yesAkademisk Kvarter, 2020
In the last few years, a new type of hero has emerged in computer games: the father, who has sole responsibility for a child. In this article, three action-adventure computer games are analyzed to explore how fatherhood extends the notion of masculinity ...
Thessa Jensen, Søren Hommel Østerlund
doaj   +1 more source

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