Results 21 to 30 of about 22,621,819 (277)

Corilagin Ameliorates Con A-Induced Hepatic Injury by Restricting M1 Macrophage Polarization

Frontiers in Immunology, 2022
Immune-mediated hepatic injury plays a key role in the initiation and pathogenesis of diverse liver diseases. However, treatment choice for immune-mediated hepatic injury remains limited.
Fenglian Yan, Fenglian Yan, Dalei Cheng, Dalei Cheng, Haiyan Wang, Haiyan Wang, Min Gao, Junfeng Zhang, Junfeng Zhang, Hongyan Cheng, Hongyan Cheng, Changying Wang, Changying Wang, Hui Zhang, Hui Zhang, Huabao Xiong, Huabao Xiong   +16 more
doaj   +1 more source

CP-25 exerts a protective effect against ConA-induced hepatitis via regulating inflammation and immune response

Frontiers in Pharmacology, 2022
Hepatitis is a complex multifactorial pathological disorder, which can eventually lead to liver failure and even potentially be life threatening. Paeoniflorin-6′-O-benzene sulfonate (CP-25) has proven to have critical anti-inflammatory effects in ...
Nan Li, Jing-Jing Wu, Jing-Jing Wu, Meng Qi, Zi-Ying Wang, Sheng-Nan Zhang, Xiu-Qin Li, Ting-Ting Chen, Mei-Fang Wang, Ling-Ling Zhang, Wei Wei, Wu-Yi Sun   +11 more
doaj   +1 more source

Conformational Changes in Concanavalin A [PDF]

Journal of Biological Chemistry, 1971
Abstract The circular dichroic spectrum of homogeneous concanavalin A shows changes in the near ultraviolet upon specific binding of α-methyl-d-mannoside. The far ultraviolet spectrum shows no evidence of α helical structure but most closely resembles the spectrum of the model for type II-β structure, poly-S-carboxymethyl-l-cysteine.
Gerald M. Edelman, Mollie N. Pflumm, John L. Wang   +2 more
openaire   +2 more sources

Reversibility of cell surface label rearrangement [PDF]

, 1976
Cell surface labeling can cause rearrangements of randomly distributed membrane components. Removal of the label bound to the cell surface allows the membrane components to return to their original random distribution, demonstrating that label is ...
Brown, Susan Smith, Revel, Jean-Paul
core   +1 more source

New synchronization method for Plasmodium falciparum [PDF]

, 2010
<b>Background</b>: Plasmodium falciparum is usually asynchronous during in vitro culture. Although various synchronization methods are available, they are not able to narrow the range of ages of parasites.
Abhinav Sinha, C Lambros, EA Nillni, G Pasvol, Georgina S Humphreys, HC Hoppe, J Inselburg, J Lelievre, JA Naughton, JB Jensen, JD Haynes, JD Haynes, JE Mrema, Jonathan M Mwangi, Lisa C Ranford-Cartwright, SB Aley, SY Ahn, W Trager   +17 more
core   +4 more sources

Differences in the signaling pathways of α1A- and α1B-adrenoceptors are related to different endosomal targeting [PDF]

, 2013
Aims: To compare the constitutive and agonist-dependent endosomal trafficking of α1A- and α1B-adrenoceptors (ARs) and to establish if the internalization pattern determines the signaling pathways of each subtype.
A Hirasawa, AC Hanyaloglu, AL Lattion, B Lei, BL Wolfe, C Moyano, C Stenbergen, CD Wright, D Calebiro, D Chalothorn, D Diviani, D Gesty-Palmer, D Wu, DM Perez, DP Morris, DP Morris, E Oliver, EJ Adie, EJ Adie, Elena Carceller, F Liu, Fermí Montó, Graeme Milligan, Ian Christie McGrath, James Porter, JB Morris, JD Pediani, JD Pediani, JL Benovic, John Pediani, KA DeFea, L Stanasila, LM Luttrell, M von Zastrow, María Antonia Noguera, MC Lyssand JS De Fino, Miguel Pérez-Aso, MW Lee, MY Tsang, P Lajoie, PA Patel, Pilar D’Ocon, RH Oakley, RR Price, S Ahn, S Alexander, S Keffel, S Mhaouty-Kodja, S Terrillon, SK Shenoy, SM DeWire, SS Ferguson, TL Theroux, Vanessa Segura, Y Huang   +54 more
core   +6 more sources

Comparison of Concanavalin a-Induced Murine Autoimmune Hepatitis Models

Cellular Physiology and Biochemistry, 2018
Background/Aims: Autoimmune hepatitis (AIH) is a chronic necroinflammatory disease of the liver whose pathogenic mechanisms have not yet been elucidated.
Tinghong Ye, Tingting Wang, Xiaoxue Yang, Xiaoli Fan, Mao-yao Wen, Yi Shen, X. Xi, R. Men, Li Yang   +8 more
semanticscholar   +1 more source

Eradication of Candida albicans persister cell biofilm by the membranotropic peptide gH625 [PDF]

, 2020
Biofilm formation poses an important clinical trouble due to resistance to antimicrobial agents; therefore, there is an urgent demand for new antibiofilm strategies that focus on the use of alternative compounds also in combination with conventional ...
D'Alterio, A., de Alteriis, E., De Natale, A., Falanga, A., Galdiero, E., Galdiero, S., Guida, M., Lombardi, L., Siciliano, A.   +8 more
core   +1 more source

Magnesium isoglycyrrhizinate positively affects concanavalin A-induced liver damage by regulating macrophage polarization

Food and Agricultural Immunology, 2018
The deficient functional polarization of macrophages is implicated in the disease progression of autoimmune hepatitis (AIH). This study aims to evaluate the impact of Magnesium isoglycyrrhizinate (MgIG) on concanavalin A (Con A)-induced hepatitis in a ...
Rui Lin, Yun Liu, Meiyu Piao, Yan Song
doaj   +1 more source

The Inositol- 1,4,5=Trisphosphate System Is Involved in Rapid Effects of Aldosterone in Human Mononuclear Leukocytes [PDF]

, 1993
There is increasing evidence for rapid steroid action on electrolyte transport in human mononuclear leukocytes (HML). In HML, aldosterone stimulates the Na+/H+ antiporter within a few minutes. Because a variety of hormones and growth factors activate the
Aktas, Janet, Christ, Michael, Eisen, Christoph, Theisen, Karl, Wehling, Martin   +4 more
core   +1 more source