Results 21 to 30 of about 74,223 (272)

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

Hepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu, Xiude Fan, Megan R. McMullen, Tatsunori Miyata, Adam Kim, Vai Pathak, Jianguo Wu, Le Z. Day, Josiah E. Hardesty, Nicole Welch, Jaividhya Dasarathy, Daniela S. Allende, Arthur J. McCullough, Jon M. Jacobs, Daniel M. Rotroff, Srinivasan Dasarathy, Laura E. Nagy   +16 more
wiley   +1 more source

The Inositol- 1,4,5=Trisphosphate System Is Involved in Rapid Effects of Aldosterone in Human Mononuclear Leukocytes [PDF]

, 1993
There is increasing evidence for rapid steroid action on electrolyte transport in human mononuclear leukocytes (HML). In HML, aldosterone stimulates the Na+/H+ antiporter within a few minutes. Because a variety of hormones and growth factors activate the
Aktas, Janet, Christ, Michael, Eisen, Christoph, Theisen, Karl, Wehling, Martin   +4 more
core   +1 more source

Effect of concanavalin a on phagocytosis by macrophages [PDF]

FEBS Letters, 1974
Rachel Goldman
openalex   +5 more sources

Construction and function analysis of the LncRNA-miRNA-mRNA competing endogenous RNA network in autoimmune hepatitis

BMC Medical Genomics, 2022
Research Highlights It was the first time to explore the disorder of ceRNA network involved in the pathogenesis of AIH. The co-expression relationship between the differentially expressed lncRNAs, miRNAs and mRNAs were predicted. The potential biological
Zhencheng Li, Ying Liu, Yiwen Hou, Zhurong Li, Chen Chen, Huiqin Hao, Yang Liu   +6 more
doaj   +1 more source

Platelet-collagen adhesion: evidence for participation of antigenically distinct entities. [PDF]

, 1984
Univalent antibody fragments prepared from a rabbit antiserum raised against whole human platelets completely inhibited adhesion of platelets to immobilized trimeric collagen in a defined, Mg2+-dependent, adhesion assay.
Barondes, SH, Shadle, PJ
core   +2 more sources

Magnesium isoglycyrrhizinate positively affects concanavalin A-induced liver damage by regulating macrophage polarization

Food and Agricultural Immunology, 2018
The deficient functional polarization of macrophages is implicated in the disease progression of autoimmune hepatitis (AIH). This study aims to evaluate the impact of Magnesium isoglycyrrhizinate (MgIG) on concanavalin A (Con A)-induced hepatitis in a ...
Rui Lin, Yun Liu, Meiyu Piao, Yan Song
doaj   +1 more source

MULTIPLEX EVALUATION OF ConA-INDUCED PRODUCTION OF TWELVE CYTOKINES IN THE CULTURES OF MONONUCLEAR CELLS FROM PERIPHERAL BLOOD OF HEALTHY SUBJECTS

Медицинская иммунология, 2014
. The goal of this work was a multiplex single-step evaluation of the levels of stimulated cytokine production in the supernates of cultivated mononuclear cells from healthy Caucasian individuals.
V. I. Konenkov, V. V. Avdoshina, I. G. Rakova, M. V. Smolninkova, E. L. Gelfgat   +4 more
doaj   +1 more source

New Insight into the Concanavalin A-Induced Apoptosis in Hepatocyte of an Animal Model: Possible Involvement of Caspase-Independent Pathway

Molecules, 2023
Concanavalin A (Con A) is known to be a T-cell mitogen and has been shown to induce hepatitis in mice through the triggering of conventional T cells and NKT cells.
Xiangli Zhao, Cheng Fu, Lingjuan Sun, Hao Feng, Peiling Xie, Meng Wu, Xiaosheng Tan, Gang Chen   +7 more
doaj   +1 more source

On the selection and design of proteins and peptide derivatives for the production of photoluminescent, red-emitting gold quantum clusters [PDF]

, 2013
Novel pathways of the synthesis of photoluminescent gold quantum clusters (AuQCs) using biomolecules as reactants provide biocompatible products for biological imaging techniques.
A Baksi, A Harriman, A Retnakumari, AM Smith, BĐ Glišić, BĐ Glišić, C Giulivi, CAJ Lin, CAJ Lin, CF Shaw III, CL Liu, CV Durgadas, D Toroz, DM Chevrier, F Wen, G Mező, GA Simms, GS Harms, H Kawasaki, H Kawasaki, H Schmidbaur, H Tsunoyama, H Wei, J Xie, J Xie, JS Mohanty, K Chaudhari, L Shang, L Shang, M Zhu, MAH Muhammed, MAH Muhammed, MS Devadas, PK Xavier, PL Xavier, R Hamouda, S Link, S Si, TH Chen, X Wen, X Yuan, X Yuan, XL Guével, Y Negishi, Y Shichibu, Y Shichibu, Y Wang, YH Lin, YN Tan   +48 more
core   +2 more sources

Niosomes and polymeric chitosan based vesicles bearing transferrin and glucose ligands for drug targeting [PDF]

, 2000
PURPOSE: To prepare polymeric vesicles and niosomes bearing glucose or transferrin ligands for drug targeting. METHODS: A glucose-palmitoyl glycol chitosan (PGC) conjugate was synthesised and glucose-PGC polymeric vesicles prepared by sonication of ...
Couet, W., Dufès, Christine, Gray, A.I., Olivier, J.C., Schätzlein, A.G., Tetley, L., Uchegbu, I.F., Watson, D.G.   +7 more
core   +1 more source