Results 71 to 80 of about 1,412,249 (275)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
以翻轉式概念構圖提升學生閱讀理解能力之研究 The Flip Concept Map in Relation to Student’s Reading Comprehension Skills
Journal of Curriculum Studies, 2016 本研究以翻轉式概念構圖為教學策略，期望能提升學生的閱讀理解能力。研究對象為新北市某國小五年級學生，以立意取樣選取兩個班級作為實驗組及控制組，實驗組教師運用翻轉式概念構圖進行教學，控制組教師以傳統講述式進行大意教學。本研究採準實驗研究設計，歷時10週，共10堂課（400分鐘），研究結果發現，實驗組經由翻轉式概念構圖的教學，在「提取訊息」與「推論訊息」沒有顯著差異，但在「詮釋整合」與「比較評估」的能力明顯優於控制組，且實驗組之中的高學習成效學生經過實驗後，在「推論訊息」能力上與低學習成效學生沒有顯著差異 ...
吳佳娣 Chia-Ti Wu +3 more
doaj +1 more source
Battery Degradation Maps for Power System Optimization and as a Benchmark Reference
, 2017 This paper presents a novel method to describe battery degradation. We use the concept of degradation maps to model the incremental charge capacity loss as a function of discrete battery control actions and state of charge.
Andersson, Göran, Fortenbacher, Philipp
core +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Mapping the e-Learning Assessment Domain: Concept Maps for Orientation and Navigation
, 2005 Concept or Topic Maps have long been used as a method of categorizing and organizing information about a domain. Building them can help people conceptualize an area and spot trends or gaps, and as a presentation method they quickly provide an overview ...
Bailey, Christopher +11 more
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Motriz: Revista de Educacao FisicaAim: To evaluate the use of CMAP tools® software as a teaching strategy of skeletal muscle components and contraction in undergraduates students of physical education. Methods: Nineteen students from the discipline of fundamentals of human physiology of
Luis Carlos Jacinto +2 more
doaj +1 more source