Results 61 to 70 of about 8,154,104 (309)

Ingredients for change: revisiting a conceptual framework [PDF]

open access: yesQuality and Safety in Health Care, 2002
Finding ways to deliver care based on the best possible evidence remains an ongoing challenge. Further theoretical developments of a conceptual framework are presented which influence the uptake of evidence into practice. A concept analysis has been conducted on the key elements of the framework--evidence, context, and facilitation--leading to ...
Rycroft-Malone, J.   +6 more
openaire   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Promoting conceptual change regarding infinity in high school mathematics teachers through a workshop

open access: yesJournal on Mathematics Education
This report delineates the outcomes of an intervention conducted with in-service high school educators, focusing on elucidating three distinct scenarios within geometric and arithmetic domains: the infinitely large, infinitely numerous, and ...
Irving Aarón Díaz-Espinoza   +2 more
doaj   +1 more source

Conceptualizing change in organizational cognition

open access: yesInternational Journal of Organization Theory & Behavior, 2021
PurposeSecchi and Cowley (2016, 2018) propose a Radical approach to Organizational Cognition (ROC) as a way of studying cognitive processes in organizations. What distinguishes ROC from the established research on Organizational Cognition is that it remains faithful to radical, anti-representationalist principles of contemporary cognitive science ...
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

A conceptual change approach to professional development of university teachers?

open access: yes, 2018
The increasing emphasis on the quality of higher education has placed higher demands on teachers’ professional development. Conceptual change approach to teacher development, namely, attempts to change teachers’ frameworks for conceptualising teaching ...
Zeng, M
core  

Understanding pre-service teacher conceptual change through slowmation animation [PDF]

open access: yes, 2012
This paper is an exploration of conceptual change. It reports on a study which utilised Hewson and Lemberger’s (2000) Conceptual Status Elements, and explores the unique contribution of Slowmation Animation in the conceptual learning of pre-service ...
Kidman, Gillian   +2 more
core  

Beyond Evidence-Based Belief Formation: How Normative Ideas Have Constrained Conceptual Change Research

open access: yesFrontline Learning Research, 2013
The cognitive sciences, including psychology and education, have their roots in antiquity. In the historically early disciplines like logic and philosophy, the purpose of inquiry was normative. Logic sought to formalize valid inferences, and the various
Stellan Ohlsson
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Training As Exchange And Negotiation Of Knowledge: An Online And In Presence

open access: yesJe-LKS: Journal of E-Learning and Knowledge Society, 2009
We propose a socio-constructivist conception of training, presenting a model of teaching-learning that we have used in traditional and online context at the University of Macerata.
Paola Nicolini, Tamara Lapucci
doaj   +1 more source

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